Lab Papers (GRASP)

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Conference Paper

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Copyright 2008 IEEE. Reprinted from:

Julius, A.A.; Imielinski, M.; Pappas, G.J., "Metabolic networks analysis using convex optimization," Decision and Control, 2008. CDC 2008. 47th IEEE Conference on , vol., no., pp.762-767, 9-11 Dec. 2008


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Metabolic networks map the biochemical reactions in a living cell to the flow of various chemical substances in the cell, which are called metabolites. A standard model of a metabolic network is given as a linear map from the reaction rates to the change in metabolites concentrations. We study two problems related to the analysis of metabolic networks, the minimal network problem and the minimal knockout problem.


optimisation, biochemical reactions, chemical substances, convex optimization, metabolic networks analysis, metabolites concentrations, minimal knockout problem, minimal network problem



Date Posted: 06 October 2009