This paper outlines the particular demands that multiple trauma makes on systems designed to provide appropriate decision support, and the ways that these demands are currently being met in our system, TraumAID. The demands follow from: (1) the nature of trauma and the procedures used in its diagnosis, (2) the need to adjust diagnostic and therapeutic procedures to available resource levels, (3) the role of anatomy in trauma and the need for anatomical reasoning, (4) the role of non-specialists in managing trauma, and (5) the competing demands of multiple injuries and the consequent need for planning. We believe that these demands are not unique to multiple trauma, so that the paper may be of general interest to expert system research and development.