Actively tuning mechanical properties in soft robots is now feasible due to advancements in soft actuation technologies. In soft manipulators, these novel actuators can be distributed over the robot body to allow greater control over its large number of degrees of freedom and to stabilize local deformations against a range of disturbances. In this paper, we present a hierarchical policy for stiffness control for such a class of soft manipulators. The stiffness changes induce desired deformations in each segment, thereby influencing the manipulator’s end-effector position. The algorithm can be run as an online controller to influence the manipulator’s stable states – as we demonstrate in simulation – or offline as a design algorithm to optimize stiffness distributions – as we showcase in a hardware demonstration. Our proposed hierarchical control scheme is agnostic to the stiffness actuation method and can extend to other soft manipulators with nonuniform stiffness distributions.