Sakar, Mahmut Selman

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2009 - 20102
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  • Publication
    Single Cell Manipulation using Ferromagnetic Composite Microtransporters
    (2010-01-29) Sakar, Mahmut Selman; Steager, Edward B; Pappas, George J; Kumar, Vijay; Kim, Dal Hyung; Kim, Min Jun
    For biomedical applications, such as single cell manipulation, it is important to fabricate microstructures that can be powered and controlled wirelessly in fluidic environments. In this letter, we describe the construction and operation of truly micron-sized, biocompatible ferromagnetic microtransporters driven by external magnetic fields. Microtransporters were fabricated using a simple, single step fabrication method and can be produced in large numbers. We demonstrate that they can be navigated to manipulate single cells with micron-size precision without disturbing the local environment.
  • Publication
    Harnessing bacterial power in microscale actuation
    (2009-05-12) Julius, A. Agung; Sakar, M. Selman; Kumar, Vijay; Steager, Edward; Pappas, George J; Cheang, U Kei; Kim, MinJun
    This paper presents a systematic analysis of the motion of microscale structures actuated by flagellated bacteria. We perform the study both experimentally and theoretically. We use a blotting procedure to attach flagellated bacteria to a buoyancy-neutral plate called a microbarge. The motion of the plate depends on the distribution of the cells on the plate and the stimuli from the environment. We construct a stochastic mathematical model for the system, based on the assumption that the behavior of each bacterium is random and independent of that of its neighbors. The main finding of the paper is that the motion of the barge plus bacteria system is a function of a very small set of parameters. This reduced-dimensional model can be easily estimated using experimental data. We show that the simulation results obtained from the model show an excellent match with the experimentally-observed motion of the barge.