Document Type
Journal Article
Date of this Version
6-2005
Publication Source
Animal Genetics
Volume
36
Issue
3
Start Page
265
Last Page
266
DOI
10.1111/j.1365-2052.2005.01275.x
Abstract
We identified a pedigree of Labrador retrievers (LR) that develop hereditary cataracts between 6 and 18 months of age. In humans, galactokinase deficiency is an autosomal recessive disorder characterized by juvenile onset of cataracts.1 In order to evaluate GALK1 as a candidate gene, we cloned and sequenced the canine GALK1 gene and tested a single nucleotide polymorphism (SNP) in the gene for segregation with cataracts in the LR pedigree.
Copyright/Permission Statement
This is the accepted version of the article which has been published in final form at 10.1111/j.1365-2052.2005.01275.x.
Recommended Citation
Sidjanin, D. J., McElwee, J. L., Miller, B., & Aguirre, G. D. (2005). Cloning of Canine Galactokinase (GALK1) and Evaluation as a Candidate Gene for Hereditary Cataracts in Labrador Retrievers. Animal Genetics, 36 (3), 265-266. http://dx.doi.org/10.1111/j.1365-2052.2005.01275.x
Included in
Animal Diseases Commons, Congenital, Hereditary, and Neonatal Diseases and Abnormalities Commons, Eye Diseases Commons, Medical Genetics Commons, Ophthalmology Commons, Veterinary Medicine Commons
Date Posted: 06 May 2015
This document has been peer reviewed.