Ne-cliticization has been widely discussed in Italian syntax (Burzio 1986, Belletti and Rizzi 1982, Perlmutter 1989 a.o.), with comparison to similar constructions in other Romance languages (see Cardinaletti and Giusti 2006 for an overview). In this paper, however, we propose a novel way to investigate this construction, from a more cross-linguistic perspective. More specifically, we show that there are a number of similarities between (quantitative) ne-cliticization and split-topicalization, which is attested in many languages such as German and Japanese, and we propose a unified account of the two constructions, based on Zamparelli's (2000) and Ott's (2011) proposals on those constructions.