Deep learning-based generative network modeling for development of brain structural connectivity
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School of Engineering and Applied Science::Department of Bioengineering::Departmental Papers (BE)
Degree type
Discipline
Biomedical Engineering and Bioengineering
Computer Sciences
Neuroscience and Neurobiology
Computer Sciences
Neuroscience and Neurobiology
Subject
Autism
Development
Machine Learning
DTI
Varational Autoencoder
Structural Connectivity
Generative Network Modeling
Development
Machine Learning
DTI
Varational Autoencoder
Structural Connectivity
Generative Network Modeling
Funder
Grant number
Copyright date
2022-06
Distributor
Related resources
Author
Shen, Rui Sherry
Osmanlıoğlu, Yusuf
Parker, Drew
Aunapu, Darien
Tunç, Birkan
Yerys, Benjamin E.
Verma, Ragini
Contributor
Abstract
Brain networks are refined in the transition from childhood to adulthood. Our understanding of wiring mechanisms underlying development, however, remains very limited. Prior work has tested several predefined wiring models and suggested increased connectivity among nodes sharing similar neighbors in addition to cost minimization. While illuminating, this hypothesis-driven approach is prone to missing unforeseen network features and is biased by the researcher’s deductive thinking. Here we present a novel deep learning-based generative network model (Deep GNM) to infer developmental mechanisms in network formation in a data-informed fashion
Advisor
Date of presentation
2022-06
Conference name
The Organization for Human Brain Mapping (OHBM)
Conference dates
2022-06
Conference location
Glasgow, Scotland, United Kingdom