Critical Issues Concerning Research Involving Decisionally Impaired Persons
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This is a working paper prepared by staff to the Human Subjects Subcommittee of the National Bioethics Advisory Commission (NBAC). At the request of the subcommittee, the paper attempts to set out the critical issues facing the commissioners concerning the recruitment and participation in clinical research of those who are decisionally impaired.
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Reprinted from Research Involving Persons with Mental Disorders That May Affect Decisionmaking Capacity, National Bioethics Advisory Commission, Volume 2, March 1999, pages 51-57. NOTE: At the time of publication, author Jonathan D. Moreno was affiliated with the University of Virginia. Currently March 2007, he is a faculty member in the Department of Bioengineering at the University of Pennsylvania.