This research looks at the intersection of two fields: modern supply chain logistics and technologies and natural disaster relief. This research aims to examine the application of blockchain and different technologies used in last-mile logistics in the relief of natural disasters. We conducted a robust literature review to understand modern supply chain technologies and advancements and current humanitarian organization operations, in addition to interviews and data collection to understand the feasibility of incorporation. Our findings recommend that individual humanitarian organizations could benefit from the adoption of blockchain and further uses of last-mile logistics to aid in the relief of natural disasters, but should be examined on a case-by-case basis. Through expert interviews, data collection, and a robust literature review, it was understood that the costs for adopting blockchain and different last mile logistics may outweigh the benefits, but it was found that there are numerous advantages to adopting the techniques. This study contributes to an essential field of research because natural disasters are becoming more frequent in the United States.