An attempt is made in this thesis to investigate certain aspects of early American Protestantism in the Arab Middle East. The research encompasses a period of one century: 1820-1920. These dates mark the initiation of American Protestantism in the Arab Middle East until the close of the First World War, which brought about a number of changes in the Arab world which vitally affected American Protestant work. The fact that the Arab world now came under domination and influence of western Christian nations, after being under Moslem rule for centuries, was of extreme importance. Thus the period 1820-1920 generally marks an epoch of American Protestantism in the Arab world.