Extensions in human longevity are prompting a growing interest in maximizing healthspan, or the number of years of life unencumbered by the chronic diseases of old age. This chapter reviews recent research on healthy life extension, including several measures and determinants of longer healthspans. We also provide an overview of recent efforts by medical and business enterprises to enhance longevity and healthspan, followed by a discussion of policy and workplace options to foster healthier lives. Such efforts hold the promise of improving quality of life, expanding labor supply, and lowering the cost of health care costs associated with population aging.