LMNA is a gene involved in the formation of nuclear lamina. Nuclear lamina provides support to the structure of the cell. The two types of lamin are type A and type B. The degradation of lamin A/C, a type A lamin, can lead to genome instability. Currently, little is known about the role of LMNA in gene regulation. Moreover, cancer cells have irregular lamin A/C expression. This project looked at LMNA by cloning the pmk453_BSD_P2A_GFP_FKBP_Lamin A - N terminal plasmid in order to transfect K562 cells and visualize the localization of lamin A/C in the cell and degrade the protein using dTAG to determine its function. Successful cloning of the plasmid was confirmed by Plasmidsaurus. The results of the dTAG show that the protein was successfully degraded and lamin A/C is localized around the nucleus of the cell.