Date of Award
Spring 5-28-2014
Degree Type
Thesis
Degree Name
MSOB (Master of Science in Oral Biology)
Primary Advisor
Denis F. Kinane, BDS, PhD
Abstract
In this study we showed TLR2 CpG promoter methylation in periodontitis affected human gingival tissues and in primary human gingival epithelial cells chronically stimulated with P. gingivalis that may instigate epithelial dysbiosis that may create a unique pathogen niche in the gingival crevice and susceptibility to periodontitis.
Recommended Citation
Abdolhosseini, Mahsa, "Epigenetic Changes in the Innate Response of Gingival Epithelium" (2014). Dental Theses. 10.
https://repository.upenn.edu/dental_theses/10