Date of Award
MSOB (Master of Science in Oral Biology)
Denis F. Kinane, BDS, PhD
In this study we showed TLR2 CpG promoter methylation in periodontitis affected human gingival tissues and in primary human gingival epithelial cells chronically stimulated with P. gingivalis that may instigate epithelial dysbiosis that may create a unique pathogen niche in the gingival crevice and susceptibility to periodontitis.
Abdolhosseini, Mahsa, "Epigenetic Changes in the Innate Response of Gingival Epithelium" (2014). Dental Theses. 10.