Departmental Papers (CIS)

Date of this Version

January 2002

Document Type

Journal Article

Abstract

The authors argue for the need to model and analyze biological networks at molecular and cellular levels. They propose a computational toolbox for biologists. Central to their approach is the paradigm of hybrid models in which discrete events are combined with continuous differential equations to capture switching behavior.

Publication Source

Computing in Science and Engineering

Volume

4

Issue

1

Start Page

20

Last Page

31

DOI

10.1109/5992.976434

Copyright/Permission Statement

© 2002 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.

Keywords

biocomputing, biomolecular electronics, discrete event simulation, stochastic systems, agents, biological networks, biomolecular networks, cellular levels, computational toolbox, discrete events, genetic circuits, hybrid models, modes, molecular levels, switching behavior

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Date Posted: 30 April 2005

This document has been peer reviewed.