Document Type

Working Paper

Date of this Version



DL-methionine is an important feed additive for poultry and swine diets. The amino acid is not produced by animals so it can only be obtained through diet. Methionine is important for protein growth and helps the health of livestock. Recent increase in meat consumption in Latin America and Asia, along with a growing consumer concern of animal welfare, has driven a growth in the methionine market. The methionine market is predicted to continue to grow for at least another five years (Methionine Market 2019). The proposed design is for a process that produces DL-methionine by fermentation with the bacteria, Corynebacterium glutamicum. The plant has a capacity of 250 kilotonnes/year and will be located in Cedar Rapids, IA. According to a 20 year profitability analysis, it has an estimated IRR of 16.43% and in 2042 it has an NPV of $5,650,200. In the third production year, the ROI will be 25.97%. The process begins with an aerobic fermentation, where the bacterial cells are grown up on a lab scale and then transferred into industrial scale pre-seed fermenters, seed fermenters, and then production fermenters. In order to produce feed grade DLM, the process after fermentation goes through heating, separation, triple effect evaporation, crystallization, and finally, drying. The final DLM product is 99% dry and 99% pure and will be sold for $3.60/kg.



Date Posted: 11 May 2020