Date of this Version
Alzheimer's & Dementia
At a symposium convened on March 8, 2007 by the Institute on Aging at the University of Pennsylvania, researchers from the University’s Schools of Medicine and Veterinary Medicine explored the convergence of aging research emerging from the two schools. Studies in human patients, animal models, and companion animals have revealed different but complementary aspects of the aging process, ranging from fundamental biologic aspects of aging to the treatment of age-related diseases, both experimentally and in clinical practice. Participants concluded that neither animal nor human research alone will provide answers to most questions about the aging process. Instead, an optimal translational research model supports a bidirectional flow of information from animal models to clinical research.
NOTICE: This is the author’s version of a work that was accepted for publication in Alzheimer's & Dementia. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms, may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Alzheimer's & Dementia, 4, 1, 10.1016/j.jalz.2007.09.007.
organ specific mechanisms of aging in humans and animals, model systems for aging research, normal aging, aging related diseases
Trojanowski, J. Q., Hendricks, J. C., Jedrziewski, K., Johnson, F., Michel, K. E., Hess, R. S., Cancro, M. P., Sleeper, M. M., Pignolo, R., Teff, K. L., Aguirre, G. D., Lee, V., Lawler, D. F., Pack, A. I., & Davies, P. F. (2008). Exploring Human/Animal Intersections: Converging Lines of Evidence in Comparative Models of Aging. Alzheimer's & Dementia, 4 (1), 1-5. http://dx.doi.org/10.1016/j.jalz.2007.09.007
Date Posted: 06 May 2015
This document has been peer reviewed.