Document Type
Journal Article
Date of this Version
12-1-1980
Publication Source
American Journal of Pathology
Volume
101
Issue
3
Start Page
657
Last Page
674
Abstract
Three cats with feline arylsulfatase-B-deficient mucopolysaccharidosis were studied by light and transmission electron microscopy. Membrane-bound cytoplasmic inclusions were present in hepatocytes, bone marrow granulocytes, vascular smooth muscle cells, and fibroblasts in skin, cornea, and cardiac valves. Central nervous system lesions were restricted to mild ventricular dilatation, perithelial cell vacuolation, and, in one animal, cord compression by vertebral exostoses. The lesions in these cats closely resembled those described in human patients with mucopolysaccharidosis VI (Maroteaux-Lamy syndrome).
Copyright/Permission Statement
Reproduced from Am J Pathol 1980, 101(3): 657-674 with permission from the American Society for Investigative Pathology. The archived version of this article can also be found online at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1903664/
Recommended Citation
Haskins, M. E., Aguirre, G. D., Jezyk, P. F., & Patterson, D. F. (1980). The Pathology of the Feline Model of Mucopolysaccharidosis VI. American Journal of Pathology, 101 (3), 657-674. Retrieved from https://repository.upenn.edu/vet_papers/17
Date Posted: 19 August 2013
This document has been peer reviewed.
Comments
PMCID: PMC1903664