Document Type

Journal Article

Date of this Version

12-1-1980

Publication Source

American Journal of Pathology

Volume

101

Issue

3

Start Page

657

Last Page

674

Abstract

Three cats with feline arylsulfatase-B-deficient mucopolysaccharidosis were studied by light and transmission electron microscopy. Membrane-bound cytoplasmic inclusions were present in hepatocytes, bone marrow granulocytes, vascular smooth muscle cells, and fibroblasts in skin, cornea, and cardiac valves. Central nervous system lesions were restricted to mild ventricular dilatation, perithelial cell vacuolation, and, in one animal, cord compression by vertebral exostoses. The lesions in these cats closely resembled those described in human patients with mucopolysaccharidosis VI (Maroteaux-Lamy syndrome).

Copyright/Permission Statement

Reproduced from Am J Pathol 1980, 101(3): 657-674 with permission from the American Society for Investigative Pathology. The archived version of this article can also be found online at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1903664/

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PMCID: PMC1903664

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Date Posted: 19 August 2013

This document has been peer reviewed.