Statistics Papers

Document Type

Journal Article

Date of this Version

2012

Publication Source

Journal of the American Statistical Association

Volume

107

Issue

498

Start Page

530

Last Page

541

DOI

10.1080/01621459.2012.655954

Abstract

An experimental unit is an opportunity to randomly apply or withhold a treatment. There is interference between units if the application of the treatment to one unit may also affect other units. In cognitive neuroscience, a common form of experiment presents a sequence of stimuli or requests for cognitive activity at random to each experimental subject and measures biological aspects of brain activity that follow these requests. Each subject is then many experimental units, and interference between units within an experimental subject is, likely, in part because the stimuli follow one another quickly and in part because human subjects learn or become experienced or primed or bored as the experiment proceeds. We use a recent functional magnetic resonance imaging (fMRI) experiment concerned with the inhibition of motor activity to illustrate and further develop recently proposed methodology for inference in the presence of interference. A simulation evaluates the power of competing procedures.

Copyright/Permission Statement

This is an Accepted Manuscript of an article published by Taylor & Francis in Journal of the American Statistical Association on 20 Mar 2012, available online: http://wwww.tandfonline.com/10.1080/01621459.2012.655954.

Keywords

attributable effects, interference between units, placements, randomized experiment

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Date Posted: 27 November 2017