
Statistics Papers
Document Type
Journal Article
Date of this Version
2012
Publication Source
Journal of the American Statistical Association
Volume
107
Issue
498
Start Page
530
Last Page
541
DOI
10.1080/01621459.2012.655954
Abstract
An experimental unit is an opportunity to randomly apply or withhold a treatment. There is interference between units if the application of the treatment to one unit may also affect other units. In cognitive neuroscience, a common form of experiment presents a sequence of stimuli or requests for cognitive activity at random to each experimental subject and measures biological aspects of brain activity that follow these requests. Each subject is then many experimental units, and interference between units within an experimental subject is, likely, in part because the stimuli follow one another quickly and in part because human subjects learn or become experienced or primed or bored as the experiment proceeds. We use a recent functional magnetic resonance imaging (fMRI) experiment concerned with the inhibition of motor activity to illustrate and further develop recently proposed methodology for inference in the presence of interference. A simulation evaluates the power of competing procedures.
Copyright/Permission Statement
This is an Accepted Manuscript of an article published by Taylor & Francis in Journal of the American Statistical Association on 20 Mar 2012, available online: http://wwww.tandfonline.com/10.1080/01621459.2012.655954.
Keywords
attributable effects, interference between units, placements, randomized experiment
Recommended Citation
Luo, X., Small, D. S., Li, C. R., & Rosenbaum, P. R. (2012). Inference With Interference Between Units in an fMRI Experiment of Motor Inhibition. Journal of the American Statistical Association, 107 (498), 530-541. http://dx.doi.org/10.1080/01621459.2012.655954
Date Posted: 27 November 2017