Statistics Papers

Document Type

Journal Article

Date of this Version

1997

Publication Source

The Annals of Statistics

Volume

25

Issue

6

Start Page

2345

Last Page

2367

DOI

10.1214/aos/1030741076

Abstract

It is shown that the standard two one-sided tests procedure for bioequivalence is a biased test. Better tests exist. In this paper, an unbiased α-level test and other tests which are uniformly more powerful than the two one-sided tests procedure are constructed. Its power can be noticeably larger than that of the α-level two one-sided tests procedure.

Keywords

two one-sided tests procedure, uniformly more powerful, pharmocokinetic parameters

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Date Posted: 27 November 2017

This document has been peer reviewed.