This tutorial aims to help you teach yourself enough of the Matlab􏱈 programming language to get started on physical modeling, and particularly the problems appearing in Physical Models of Living Systems (Nelson, 2015). This is not an official publication of The MathWorks, Inc. We attempt to maintain it, but no claim is made that every suggestion made here will work properly with future versions of Matlab. This is a free online document. Code listings that appear in this document, errata, and more can be found online via http://www.physics.upenn.edu/biophys/PMLS/Student ; code can also be accessed by following the links that appear in the far left margins of this document. A companion to this tutorial covers similar techniques, but with the Python programming language (Kinder & Nelson, 2018).