Department of Physics Papers

Document Type

Journal Article

Date of this Version

12-2007

Publication Source

Current Opinion in Colloid & Interface Science

Volume

12

Issue

6

Start Page

307

Last Page

313

DOI

10.1016/j.cocis.2007.07.015

Abstract

Tethered particle motion is an experimental technique to monitor conformational changes in single molecules of DNA in real time, by observing the position fluctuations of a micrometer-size particle attached to the DNA. This article reviews some recent work on theoretical problems inherent in the interpretation of TPM experiments, both in equilibrium and dynamical aspects.

Keywords

Tethered motion, Hidden Markov, DNA conformation, DNA looping, Single-particle tracking

Included in

Physics Commons

Share

COinS
 

Date Posted: 01 May 2017

This document has been peer reviewed.