Department of Physics Papers

Document Type

Journal Article

Date of this Version

5-1998

Publication Source

Biophysics Journal

Volume

74

Issue

5

Start Page

2501

Last Page

2503

DOI

10.1016/S0006-3495(98)77958-5

Abstract

The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally constrained single molecules give the first direct measurement of this new material parameter. We extract its value from a recent experiment. Finally, we sketch the effect of constrained twist on entropic elasticity of DNA arising from the connection between Link, Twist, and Writhe.

Keywords

Entropic elasticity, Optical tweezers, DNA conformation

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Date Posted: 01 May 2017

This document has been peer reviewed.