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The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally constrained single molecules give the first direct measurement of this new material parameter. We extract its value from a recent experiment. Finally, we sketch the effect of constrained twist on entropic elasticity of DNA arising from the connection between Link, Twist, and Writhe.
Entropic elasticity, Optical tweezers, DNA conformation
Nelson, P. C. (1998). New Measurements of DNA Twist Elasticity. Biophysics Journal, 74 (5), 2501-2503. http://dx.doi.org/10.1016/S0006-3495(98)77958-5
Date Posted: 01 May 2017
This document has been peer reviewed.