Date of this Version
Sleep Medicine Clinics
Large-scale randomized trials of positive airway pressure (PAP) efficacy have been largely negative yet PAP adherence was notably sub-optimal across the trials. To address this limitation, evidence-based PAP adherence protocols embedded within the larger trial protocol are recommended. The complexity of such protocols will be dependent on adequacy of resources, including funding and inclusion of behavioral scientist experts on the scientific team, and trial-specific considerations (e.g., target population) and methods. Recommendations for optimizing PAP adherence in large-scale trials are set forth that address rigor and reproducibility.
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obstructive sleep apnea, continuous positive airway pressure, patient compliance, health behavior, telemedicine, health education, controlled clinical trial, behavioral economics
Sawyer, A. M., Wallace, D. M., Buenaver, L. F., Watach, A. J., Blase, A., Saconi, B., Patel, S. R., Kuna, S. T., & Punjabi, N. M. (2020). Where to Next for Optimizing Adherence in Large-scale Trials of CPAP?. Sleep Medicine Clinics, Retrieved from https://repository.upenn.edu/nrs/195
Date Posted: 27 July 2020