Date of this Version
Journal of Sleep Research
Controversy persists about whether snoring can affect atherosclerotic changes in adjacent vessels, independently of obstructive sleep apnea and other cardiovascular risk factors. This study examined the independent association between snoring and carotid artery intima-media thickness (IMT) in non-apneic snorers and non-snorers. We studied 180 non-apneic snorers and non-snorers participating in a full-night home-based sleep study. Snoring sound was measured objectively by a microphone. Based on snoring time across the night, participants were classified as non-snorers (snoring time: 0%), mild snorers (1-25%) and moderate to heavy snorers (≥25%). We measured IMT on both common carotid arteries. The three groups were matched by age, body mass index, cholesterol, blood pressure and glucose levels, using weights from generalized boosted-propensity score models. Mean carotid IMT increased with increased snoring time across the night in women: non-snorers (0.707 mm), mild (0.718 mm) and moderate to heavy snorers (0.774 mm), but not in men. Snoring during at least one-fourth of a night's sleep is associated independently with subclinical changes in carotid IMT in women only.
This is the peer reviewed version of the following article: [Kim, J. et al. (2017). Objective Snoring Time and Carotid Intima-Media Thickness in Non-Apneic Female Snorers. Journal of Sleep Research 26, no. 2: 147-150], which has been published in final form at http://dx.doi.org/10.1111/jsr.12471. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Cardiovascular Diseases, Carotid Artery Diseases, Carotid Artery, Common, Carotid Intima-Media Thickness, Case-Control Studies, Female, Humans, Male, Middle Aged, Polysomnography, Risk Factors, Sex Characteristics, Sleep, Snoring
Kim, J., Pack, A. I., Riegel, B., Chirinos, J. A., Hanlon, A., Lee, S., & Shin, C. (2016). Objective Snoring Time and Carotid Intima-Media Thickness in Non-Apneic Female Snorers. Journal of Sleep Research, 26 (2), 147-150. http://dx.doi.org/10.1111/jsr.12471
Date Posted: 06 August 2018
This document has been peer reviewed.