Neuroethics Publications

Document Type

Journal Article

Date of this Version

12-1-2006

Abstract

A common feature of the antisocial, rule-breaking behavior that is central to criminal, violent and psychopathic individuals is the failure to follow moral guidelines. This review summarizes key findings from brain imaging research on both antisocial behavior and moral reasoning, and integrates these findings into a neural moral model of antisocial behavior. Key areas found to be functionally or structurally impaired in antisocial populations include dorsal and ventral regions of the prefrontal cortex (PFC), amygdala, hippocampus, angular gyrus, anterior cingulate and temporal cortex. Regions most commonly activated in moral judgment tasks consist of the polar/medial and ventral PFC, amygdala, angular gyrus and posterior cingulate. It is hypothesized that the rule-breaking behavior common to antisocial, violent and psychopathic individuals is in part due to impairments in some of the structures (dorsal and ventral PFC, amygdala and angular gyrus) subserving moral cognition and emotion. Impairments to the emotional component that comprises the feeling of what is moral is viewed as the primary deficit in antisocials, although some disruption to the cognitive and cognitive-emotional components of morality (particularly self-referential thinking and emotion regulation) cannot be ruled out. While this neurobiological predisposition is likely only one of several biosocial processes involved in the etiology of antisocial behavior, it raises significant moral issues for the legal system and neuroethics.

Comments

© The author 2006. Published by Oxford University Press. Postprint version. Published in Social Cognitive and Affective Neuroscience, Volume 1, Issue 3, December 2006, pages 203-213. Publisher URL: http://scan.oxfordjournals.org/

NOTE: At the time of publication, author Adrian Raine was affiliated with the University of Southern California. Effective July 1, 2007, he will be a faculty member in the Department of Criminology and the Department of Psychiatry at the University of Pennsylvania.

Keywords

antisocial, psychopathy, moral, prefrontal, temporal

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Date Posted: 04 April 2007