Departmental Papers (MSE)

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Journal Article

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Coarse-grained molecular dynamics simulations are performed to obtain the phase diagram for shapes of a vesicle with a variation in temperature and pressure difference across the membrane. Various interesting vesicle shapes are found, in particular, a series of shape transformations are observed for a vesicle with an initial spherical shape, which changes to a prolate shape, then an oblate shape, and then a stomatocyte shape, with either increasing temperature or decreasing pressure difference across the membrane.


Copyright 2009 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. Reprinted in:

Pressure-temperature phase diagram for shapes of vesicles: A coarse-grained molecular dynamics study Ping Liu, Ju Li, and Yong-Wei Zhang, Appl. Phys. Lett. 95, 143104 (2009), DOI:10.1063/1.3245307 Publisher URL:


biomechanics, biomembranes, biothermics, cellular biophysics, molecular dynamics method, phase diagrams



Date Posted: 27 October 2009

This document has been peer reviewed.