Department of Microbiology Papers

 
Research in the Penn Microbiology Department focuses on infectious agents that threaten global health, with an emphasis on understanding molecular mechanisms and developing key new methods. Areas of focus include pathogenic bacteria of the airway and gut, HIV/AIDS, insect- and rodent-borne viruses, herpes viruses, papillomaviruses, emerging infectious diseases and the human microbiome. On the host side, faculty study many areas of immunology related to infection, including innate and adaptive immunity, tumor immunology and vaccine development.

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Papers from 2013

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Caspase-11 Activation in Response to Bacterial Secretion Systems That Access the Host Cytosol, Cierra N. Casson, Alan M. Copenhaver, Erin E. Zwack, Hieu T. Nguyen, Till Strowig, Bahar Javdan, William P. Bradley, Thomas C. Fung, Richard A. Flavell, Igor E. Brodsky, and Sunny Shin

Papers from 2011

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Dissection of a Type I Interferon Pathway in Controlling Bacterial Intracellular Infection in Mice, Juliane Lippmann, Holger Müller, Jan Naujoks, Christoph Tabeling, Sunny Shin, Martin Witzenrath, Katharina Hellwig, Carsten J. Kirschning, Gregory A. Taylor, Winfried Barchet, Stefan Bauer, Norbert Suttorp, Craig A. Roy, and Bastian Opitz

Papers from 2009

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Rapid Pathogen-Induced Apoptosis: A Mechanism Used by Dendritic Cells to Limit Intracellular Replication of Legionella Pneumophila, Catarina V. Nogueira, Tullia Lindsten, Amanda M. Jamieson, Christopher L. Case, Sunny Shin, Craig B. Thompson, and Craig R. Roy

Papers from 2008

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An Autonomous CDR3δ is Sufficient for γδ T Cell Recognition of the Nonclassical MHC-I T10/T22, Erin J. Adams, Pavel Strop, Sunny Shin, Yueh-Hsiu Chien, and K. Christopher Garcia

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Thymic Selection Determines γδ T Cell Effector Fate: Antigen-Naive Cells Make Interleukin-17 and Antigen-Experienced Cells Make Interferon γ, Kirk D. C Jensen, Xiaoqin Su, Sunny Shin, Luke Li, Sawsan Youssef, Sho Yamasaki, Lawrence Steinman, Takashi Saito, Richard M. Locksley, Mark M. Davis, Nicole Baumgarth, and Yueh-hsiu Chien

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Type IV Secretion-Dependent Activation of Host MAP Kinases Induces an Increased Proinflammatory Cytokine Response to Legionella pneumophila, Sunny Shin, Christopher L. Case, Kristina A. Archer, Catarina V. Nogueira, Koichi S. Kobayashi, Richard A. Flavell, Craig R. Roy, and Dario S. Zamboni

Papers from 2002

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The D0 Domain of KIR3D Acts as a Major Histocompatibility Complex Class I Binding Enhancer, Salim I. Khakoo, Ron Geller, Sunny Shin, Jomaquai A. Jenkins, and Peter Parham

Papers from 1999

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Genetic Analysis of Human Immunodefiency Virus Type I Strains in Kenya: A Comparison Using Phylogenetic Analysis and a Combinatorial Melting Assay, Kenneth E. Robbins, Leondios G. Kostrikis, Teresa M. Brown, Omu Anzala, Sunny Shin, Francis A. Plummer, and Marcia L. Kalish