This paper proposes a training toolkit for facilitators from the Cystic Fibrosis Foundation (CFF) on how to build high-quality connections (HQCs) through small group discussions to enhance the well-being of the cystic fibrosis (CF) community at scale. The relevance of initiatives for connection and relationship building is paramount to the CFF because people with CF tend to be isolated as a mechanism to prevent infections. We propose that HQCs, which are short moments characterized by shared mutuality, vitality, and positive regard, are an effective tool for facilitators to rapidly foster a sense of belonging during short, small group discussions. Our training toolkit helps the Connection and Support team at the CFF equip facilitators in three categories: high-level facilitation meta-skills, powerful beginnings and endings for sessions, and interventions that can be used during a session to deepen connections. The Connection and Support team is planning to incorporate the toolkit in their updated facilitator training. Applying HQCs in small group discussions within the CFF may increase the well-being of the facilitators, people with CF, and potentially their caregivers.