Effects of NOTCH Signaling on the Progenitor Function of iRASC to Differentiate into Other Airway Epithelial Cells
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Interdisciplinary Centers, Units and Projects::Center for Undergraduate Research and Fellowships (CURF)::Fall Research Expo
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Adult and Continuing Education
Subject
Biology, Medicine
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2025
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Suh, Ellie
Basil, Maria
Contributor
Marquis, Abigail
Basil, Maria
Abstract
The project focuses on testing the hypothesis that RAS cells can act as a progenitor for other airway epithelial cells. The methodology of the project includes using an established human embryonic stem cell (hESC) model with multiple reporter systems. A combination of immunofluorescence and quantitative reverse transcription polymerase chain reaction (q-RT-PCR) will be used to test how the NOTCH pathway affects this progenitor function.
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2025
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This project was funded by the Ruth Marcus Kanter College Alumni Society Undergraduate Research Grant