School of Veterinary Medicine
The School of Veterinary Medicine at the University of Pennsylvania was founded in 1884, and has a long-standing tradition as a global leader in veterinary medicine education, research, and clinical care, with a tradition of compassionate clinical expertise, intellectual rigor and the pursuit of innovative thinking.
Our mission at Penn Vet is to train the next generation of veterinary leaders to advance healthcare outcomes and access, ensure global health, bolster sustainable agriculture, support interdisciplinary career paths, and foster diversity, equity, and inclusion in the profession.
PublicationClinico-Pathologic Conference: Chronic Nephritis in a Bull(1961-10-15) Marshak, Robert; Buchanan, James W; Sauer, R. M PublicationPosterior Lenticonus in the Dog(1973-07-01) Aguirre, Gustavo D; Bistner, Stephen IPosterior lenticonus is a congenital defect of the posterior lenticular surface. The posterior cortical and capsular regions of the lens have a circumscribed conelike or globular protrusion of variable size. Opacities may be present in the region of the conus. The defect has been reported in man, rabbits, calves and mice. This report documents 2 cases in unrelated dogs. The possible mechanism for the formation of this defect is discussed. PublicationPersistent Left Cranial Vena Cava in Dogs: Angiocardiography, Significance, and Coexisting Anomalies(1963) Buchanan, James WPersistent left cranial venae were observed in angiocardiograms of 3 dogs at the University of Pennsylvania Veterinary Hospital. Although this vessel seldom has clinical significance, it is hoped this report will spare others the confusion caused by the first case in this series. These 3 dogs and 5 out of 7 others had significant cardiovascular anomalies in addition to persistent left cranial venae cavae. PublicationExperimental Studies on Ectopic Atrial Rhythms in Dogs(1967-05-01) Moore, E. Neil; Jomain, Serge L; Stuckey, Jackson H; Buchanan, James W; Hoffman, Brian F PublicationClinical Observations of Bone and Joint Diseases in Horses(1968) Raker, Charles WBone and joint diseases in the horse, as observed by the veterinary clinician, assume many forms frequently producing signs of lameness. The bones or joints of the limbs are most commonly affected and many factors which operate either singly or collectively produce the lesions observed. PublicationDiseases of the Pharynx(1976-06-01) Raker, Charles W PublicationEndocardial Splitting of the Left Atrium in Dogs with Hemorrhage and Hemopericardium(1964) Buchanan, James W; Kelly, Alan M PublicationDiseases of the Pharynx(1976-05-01) Raker, Charles W PublicationViral-Antibody Complexes in Canine Adenovirus Type I (CAV-1) Ocular Lesion: Leukocyte Chemotaxis and Enzyme Release(1975-07-01) Carmichael, Leland E; Medic, B. L.; Bistner, Stephen I; Aguirre, Gustavo DCanine adenovirus-type 1 (CAV-1)-antibody complexes caused severe anterior uveitis with corneal edema ("blue eye") when injected into the anterior chamber of normal dogs. The response of the anterior uvea to such immune complexes (IC) was similar to the spontaneously occurring disease. In the presence of complement (C'), IC caused release of neutrophile chemotactic factors. Following phagocytosis of IC-C', leukocytes released lysosomal enzymes, as indicated by the presence of acid phosphatase in the surrounding medium. Membrane bound viral aggregates, presumably IC, were common in neutrophiles and in macrophages that had infiltrated the anterior chamber of opaque eyes that occurred after intravenous (IV) inoculation with attenuated CAV-1. These data were incorporated into a postulated scheme for the pathogenesis of CAV-1 uveitis with corneal edema. PublicationAortic Embolism in Cats: Prevalence, Surgical Treatment and Electrocardiography(1966-10-29) Buchanan, James W; Baker, Gordan J; Hill, John DAortic embolism (caudal arterial thromboembolism) was diagnosed over a four-year-period in 14 out of 2,000 cats in a hospital clinic population (7/1,000). Including 35 cases reported in the literature, the average age of 50 cats with aortic embolism was 6-8 years (range one to 16 years). Of these, 37 were males and 13 were females. Endocarditis with thrombosis was the most frequently observed cause of aortic embolism, although aortic arteriosclerosis was reported in one cat. The clinical and pathological features of aortic embolism in five cats are described in this report. In electrocardiograms of four of these, arrhythmias or conduction disturbances were recorded. Intact emboli in the aorta and external iliac arteries were removed by abdominal aortic embolectomy in two cats within hours after the onset of posterior paralysis. Death resulted in one case from cardiac complications and in the other by euthanasia at the later date because of probably recurrent aortic embolism. In the other three cases, multiple sections of the aorta with the embolus in situ were examined, but no microscopic changes in the aortic wall were noted. Surgical removal of an aortic embolus is technically and economically feasible and is considered the treatment of choice when treatment is requested within hours after the onset of clinical signs. Although embolectomy can yield a good immediate result; the long range justification for such therapy requires further evaluation, since recurrent embolization may develop.