Medical reference work written in the late 17th century, with citations of Galen and Avicenna (for example, f. 187v) but also 16th- and 17th-century physicians such as Johannes Schenck von Grafenberg, Wilhelm Fabry, Bartholinus (probably Caspar Bartholin the Elder), and Pierre Borel (f. 3r-3v), with the work of Friedrich Hoffmann being among the latest cited (f. 9v). The manuscript is divided into three books concerning the diseases of the upper (regio animalis, f. 1r-75r), middle (regio vitalis, f. 75r-120v), and lower (regio naturalis, f. 120v-207r) regions of the body. The diseases of the upper region include headache, vertigo, epilepsy, melancholy, mania, and catarrh; of the middle region, pneumonia, phthisis, asthma, and cough; and of the lower region, stomachache, heart pain, vomiting, lacking or excess appetite, cholera, dysentery, and colic. Each disease is described in sections under the headings Causae, Differentiae, Diagnosis, Prognosis, and Curatio. Additional remedies are written by multiple hands on the pastedowns and endleaves; the endleaves are reinforced at the gutter with tape.