Objective: This article explores the ongoing relevance of cement-retained implant restorations, focusing on their contemporary rationales for their successful use. Comprehensive considerations include esthetic, positional, and occlusal factors alongside recent technological advancements designed to mitigate previous known challenges. Overview: In certain clinical scenarios, cement-retained implant restorations offer distinct advantages such as eliminating access holes for improved esthetics, particularly for malpositioned implants. Modern advancements in materials and techniques have enhanced their predictability, safety, and overall outcomes while minimizing biological risks. Conclusions: When performed within appropriate protocols, cement-retained implant restorations can effectively address diverse clinical challenges. Recent technical advancements further bolster their utility, supporting esthetic, technical, biomechanical, and biological outcomes in implant rehabilitation of the partially edentulous esthetic zone. Clinical Significance: Understanding the justifications and guidelines for cement-retained implant restorations, along with recent technological advancements, enables clinicians to optimize treatment outcomes with greater flexibility while minimizing common limitations in practice. © 2024 Wiley Periodicals LLC.