This study compares the impact of the COVID-19 pandemic and the Zika epidemic on domestic violence (DV) among women of reproductive age in Pernambuco, Brazil. We used the Ordinary Least Squares (OLS) regression on a sample of 3,423 women. We find that the effect of COVID-19 restrictions on DV was often mixed and often not-significant. In contrast, the Zika epidemic displayed a strong, consistent association with higher domestic violence, particularly for women who were pregnant. DV were reported to be significantly higher during Zika outbreaks (∗∗∗p<0.001). The results emphasize that while COVID-19 posed universal risks, health crises that intersect with and amplify gender inequalities, like Zika, may have a more profound and disproportionate impact on women's safety.