Optical Diagnostics in the Oral Cavity: An Overview

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Departmental Papers (Dental)
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Author keywords: Dental
Diagnosis
Optical
Oral MeSH: Diagnostic Imaging
Fluorescence
Humans
Lasers
Light
Mouth Diseases
Optical Devices
Spectrum Analysis
Tomography
Optical Coherence
Tooth Diseases
Transillumination EMTREE drug terms: aminolevulinic acid
aminolevulinic acid hexyl ester
aminolevulinic acid methyl ester
metvixr
photofrin
photosensitizing agent
tetrakis(3 hydroxyphenyl)chlorin
unclassified drug EMTREE medical terms: chemoluminescence
clinical feature
confocal microscopy
dental caries
diagnostic accuracy
fluorescence imaging
human
in vivo study
laser fluorescence
magnifying endoscopy
mouth cancer
mouth cavity
mouth lesion
mucosa inflammation
multiphoton microscopy
nonhuman
optical coherence tomography
oropharynxl mucositis
periodontal disease
polarization microscopy
priority journal
review
sensitivity and specificity
Dentistry
Oral Biology and Oral Pathology
Other Dentistry
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Wilder-Smith, P
Holtzman, J
Epstein, J
Le, A
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Abstract

As the emphasis shifts from damage mitigation to disease prevention or reversal of early disease in the oral cavity, the need for sensitive and accurate detection and diagnostic tools become more important. Many novel and emergent optical diagnostic modalities for the oral cavity are becoming available to clinicians with a variety of desirable attributes including: (i) non-invasiveness, (ii) absence of ionizing radiation, (iii) patient-friendliness, (iv) real-time information (v) repeatability, and (vi) high-resolution surface and subsurface images. In this article, the principles behind optical diagnostic approaches, their feasibility and applicability for imaging soft and hard tissues, and their potential usefulness as a tool in the diagnosis of oral mucosal lesions, dental pathologies, and other dental applications will be reviewed. The clinical applications of light-based imaging technologies in the oral cavity and of their derivative devices will be discussed to provide the reader with a comprehensive understanding of emergent diagnostic modalities. © 2010 John Wiley & Sons A/S.

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2010-11-01
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Oral Diseases
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At the time of publication, author A. Le was affiliated with the University of Southern California School of Dentistry. Currently, (s)he is a faculty member at the School of Dental Medicine at the University of Pennsylvania.
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