Tear Osmolarity and Dry Eye Symptoms in Women Using Oral Contraception and Contact Lenses

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dc.contributor.authorChen, Sarah P
dc.contributor.authorMassaro-Giordano, Giacomina
dc.contributor.authorPistilli, Maxwell
dc.contributor.authorSchreiber, Courtney A
dc.contributor.authorBunya, Vatinee Y
dc.date2023-05-17T22:49:55.000
dc.date.accessioned2023-05-23T00:12:57Z
dc.date.available2023-05-23T00:12:57Z
dc.date.issued2013-01-01
dc.date.submitted2019-10-01T07:11:35-07:00
dc.description.abstractPurpose—To examine the relationship between oral contraceptive pill (OCP) use, contact lens wear, and dry eye signs and symptoms in healthy young females. Methods—Fifty-two women using OCPs and forty-five women not using any form of hormonal contraception were enrolled. Medical, menstrual, and contact lens histories were obtained and dry eye symptoms were assessed using the Ocular Surface Disease Index (OSDI) and Symptom Assessment iN Dry Eye (SANDE) questionnaires. Tear osmolarity testing was performed using the TearLab™ Osmolarity System. Results—Mean age of all subjects was 26.0 ± 3.7 years. There were no significant differences in any of the measurements between the follicular and luteal phases. While SANDE scores were significantly higher in subjects with OCP and recent contact lens use (p<0.01), there were no significant differences in OSDI and tear osmolarity amongst the same subject groups. Subjects who reported both OCP and recent contact lens use had significantly higher OSDI and SANDE scores (p=0.015 and p<0.001, respectively). Conclusions—There were no differences between the phases of the menstrual cycle. Tear osmolarity was not affected by OCP or contact lens use in young females. However, the combination of OCP use and contact lens wear may increase the severity of dry eye symptoms.
dc.identifier.urihttps://repository.upenn.edu/handle/20.500.14332/41783
dc.legacy.articleid1006
dc.legacy.fields10.1097/ICO.0b013e3182662390
dc.legacy.fulltexturlhttps://repository.upenn.edu/cgi/viewcontent.cgi?article=1006&amp;context=obgyn_papers&amp;unstamped=1
dc.rightsThis is a non-final version of an article published in final form in Cornea.
dc.source.endpage4
dc.source.issue5
dc.source.journalDepartmental Papers (Obstetrics and Gynecology)
dc.source.journaltitleCornea
dc.source.peerreviewedtrue
dc.source.statuspublished
dc.source.volume32
dc.subject.otherMedicine and Health Sciences
dc.titleTear Osmolarity and Dry Eye Symptoms in Women Using Oral Contraception and Contact Lenses
dc.typeArticle
digcom.contributor.authorChen, Sarah P
digcom.contributor.authorMassaro-Giordano, Giacomina
digcom.contributor.authorPistilli, Maxwell
digcom.contributor.authorisAuthorOfPublication|email:schreibe@upenn.edu|institution:University of Pennsylvania|Schreiber, Courtney A
digcom.contributor.authorBunya, Vatinee Y
digcom.identifierobgyn_papers/5
digcom.identifier.contextkey15461154
digcom.identifier.submissionpathobgyn_papers/5
digcom.typearticle
dspace.entity.typePublication
relation.isAuthorOfPublication9564963c-1c1a-4f1d-acb3-3689bc3f27ff
relation.isAuthorOfPublication9564963c-1c1a-4f1d-acb3-3689bc3f27ff
relation.isAuthorOfPublication.latestForDiscovery9564963c-1c1a-4f1d-acb3-3689bc3f27ff
upenn.schoolDepartmentCenterDepartmental Papers (Obstetrics and Gynecology)
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