Date of Award
2012
Degree Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
Graduate Group
Neuroscience
First Advisor
Joshua I. Gold
Abstract
Making accurate predictions is one of the most critical functions of the brain. Whether made by a monkey deciding where to forage, a deer deciding which way to run, or a wall-street broker deciding how to invest, decisions are informed by expectations about possible future outcomes. These expectations are learned over time through experience and are rapidly adjusted when they fail to match observations. Here I propose and support the thesis that learning systems in the brain optimize the accuracy of predictions in a changing world, even though this necessitates becoming insensitive to incoming sensory information under some conditions. Furthermore I propose a biologically inspired model for achieving accurate predictions and suggest a novel role for the arousal system in optimally adjusting the influence of incoming sensory information. I support these theses with a series of experiments that utilize computational modeling, as well as behavioral and pupillometric measurements in humans.
Recommended Citation
Nassar, Matthew R., "A Computational Role for Arousal in Optimal Inference" (2012). Publicly Accessible Penn Dissertations. 677.
https://repository.upenn.edu/edissertations/677