Defining The Nature Of Cd8+ T Cell Responses In Lymphoid Tissues Of Hiv-1 Elite Controllers: An Implication For Hiv Cure

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Degree type
Doctor of Philosophy (PhD)
Graduate group
Cell & Molecular Biology
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CD8+ T cell
Elite controller
HIV
Lymphoid tissue
Allergy and Immunology
Cell Biology
Immunology and Infectious Disease
Medical Immunology
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2021-08-31T20:20:00-07:00
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Nguyen, Son Ngoc
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Abstract

Acquired Immunodeficiency Syndrome (AIDS) is an immunodeficiency caused by infection with Human Immunodeficiency Virus (HIV). Since its first documentation in 1981, the AIDS pandemic has claimed the lives of 32 million people worldwide. The introduction of antiretroviral therapy drugs (ART) and combined therapy in 1995 has transformed HIV infections from a “death-sentence” into a manageable and often non-fatal chronic condition. Still, no cure is available. While without ART most HIV-infected individuals (>99%) progress to AIDS, a subset of infected individuals (

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Michael R. Betts
James A. Hoxie
Date of degree
2020-01-01
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