Departmental Papers (Dental)
Date of this Version
Microbes and Infection
This review summarizes and discusses virulence mechanisms whereby Porphyromonas gingivalis can persist in the oral cavity. It is proposed that that the virulence of P. gingivalis is dependent, at least in part, upon its ability to establish a complex host-pathogen molecular crosstalk which subverts innate immunity. The sophisticated stealth and sabotage tactics used by P. gingivalis may additionally benefit co-habiting organisms occupying the same niche
©<2009> . This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
P. gingivalis, host-pathogen interactions, innate immunity, inflammation, immune evasion
Hajishengallis, G. (2009). Porphyromonas gingivalis-Host Interactions: Open War or Intelligent Guerilla Tactics?. Microbes and Infection, 11 (6-7), 637-645. http://dx.doi.org/10.1016/j.micinf.2009.03.009
Date Posted: 24 February 2022
This document has been peer reviewed.
At the time of publication, author George Hajishengallis was affiliated with the University of Louisville Health Sciences Center. Currently, he is a faculty member at the School of Dental Medicine at the University of Pennsylvania.