Departmental Papers (Dental)

Document Type

Journal Article

Date of this Version

9-1-2014

Publication Source

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Volume

116

Issue

3

DOI

10.1016/j.oooo.2013.05.023

Abstract

McCune-Albright syndrome (MAS) is a rare multisystem disorder characterized by the triad of polyostotic fibrous dysplasia (PFD), endocrine disorders and café-au-lait skin pigmentation. Ninety percent of MAS patients have FD lesions in the craniofacial area, resulting in significant orofacial deformity, dental disorders, bone pain and compromised oral health. Maxillo-mandibular FD is also associated with dental developmental disorders, malocclusion, and high caries index. There is limited data on the outcomes of dental treatments in maxillo-mandibular FD/MAS patients, because clinicians and researchers have limited access to patients, and there are concerns that dental surgery may activate quiescent jaw FD lesions to grow aggressively. This report highlights current perspectives on dental management issues associated with maxillo-mandibular FD within the context of MAS.

Copyright/Permission Statement

This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/"

Keywords

Fibrous dysplasia; McCune-Albright syndrome; dental anomalies; gene mutation; oral health

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Dentistry Commons

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Date Posted:30 July 2018