Departmental Papers (Dental)

Document Type

Review

Date of this Version

3-2014

Publication Source

Current Oral Health Reports

Volume

1

Issue

1

Start Page

34

Last Page

42

DOI

10.1007/s40496-014-0012-0

Abstract

In recent years, stem cell research in dentistry has grown rapidly with the potential application for oral and maxillofacial tissue regeneration. Mesenchymal stem cells (MSCs) from the oral and maxillofacial region are easy to access, have a high proliferation rate, multipotency, and potent immunomodulatory functions. They are excellent cell sources not only for stem cell-based therapy of dental and craniofacial diseases, but also with the potential for the treatment of other inflammatory diseases. In this review, we provide an overview of different types of MSCs that have been isolated and characterized from several origins such as dental pulp, exfoliated deciduous teeth, the periodontal ligament, the dental follicle, the dental papilla, oral mucosa, and gingiva, with the focus on the potential clinical applications for each type of dental stem cell. © 2014, Springer International Publishing AG.

Keywords

DFSCs Dental Follicle Stem Cells, DPSCs Dental Pulp Stem Cells, DSCs Dental Stem Cells, GMSCs Gingiva-Derived Mesenchymal Stem/Stromal Cells, Immunomodulation, Inflammatory Disease, MSCs Mesenchymal Stem Cells, Multipotency, PDLSCs Periodontal Ligament Stem Cells, SCAP Stem Cells From Root Apical Papilla, SHED Stem Cells From Human Exfoliated Deciduous Teeth

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Date Posted: 10 February 2023

This document has been peer reviewed.