Departmental Papers (Dental)
Date of this Version
Drug Design, Development and Therapy
In the last half-century, the development of biodegradable polymeric materials for biomedical applications has advanced significantly. Biodegradable polymeric materials are favored in the development of therapeutic devices, including temporary implants and three-dimensional scaffolds for tissue engineering. Further advancements have occurred in the utilization of biodegradable polymeric materials for pharmacological applications such as delivery vehicles for controlled/sustained drug release. These applications require particular physicochemical, biological, and degradation properties of the materials to deliver effective therapy. As a result, a wide range of natural or synthetic polymers able to undergo hydrolytic or enzymatic degradation is being studied for biomedical applications. This review outlines the current development of biodegradable natural and synthetic polymeric materials for various biomedical applications, including tissue engineering, temporary implants, wound healing, and drug delivery. © 2018 Song et al.
Drug delivery, Natural biomaterials, Synthetic biomaterials, Tissue engineering, Wound healing, Animals, Biocompatible Materials, Biomedical Research, Drug Delivery Systems, Humans, Polymers, Prostheses and Implants, Tissue Engineering, Wound Healing, alginic acid, arabinogalactan, biodegradable plastic, biomaterial, carmustine, chitin, chitosan, chlorhexidine, collagen, fibrin, gelatin, gentamicin, hyaluronic acid derivative, insulin, polyanhydride, polycaprolactone, polyester, polyhydroxyalkanoic acid, polymer, polysaccharide, polyurethan, silk, starch, biomaterial, polymer, bone graft, brain cancer, controlled drug release, drug delivery system, enzymatic degradation, human, hydrogel, insulin dependent diabetes mellitus, nonhuman, Review, sustained drug release, tissue engineering, wound healing, animal, chemistry, drug delivery system, drug effect, medical research, metabolism, prostheses and orthoses, tissue engineering, wound healing
Song, R., Murphy, M., Li, C., Ting, K., Soo, C., & Zheng, Z. (2018). Current Development of Biodegradable Polymeric Materials for Biomedical Applications. Drug Design, Development and Therapy, 12 3117-3145. http://dx.doi.org/10.2147/DDDT.S165440
Date Posted: 10 February 2023
This document has been peer reviewed.
At the time of publication, author Chenshuang Li was affiliated with the School of Dentistry, University of California. Currently, (s)he is a faculty member at the School of Dental Medicine at the University of Pennsylvania.