Departmental Papers (Dental)
Title
Milestones in Chloroplast Genetic Engineering: an Environmentally Friendly Era in Biotechnology
Document Type
Journal Article
Date of this Version
2-2002
Publication Source
Trends in Plant Science
Volume
7
Issue
2
Start Page
84
Last Page
91
Abstract
Chloroplast genomes defied the laws of Mendelian inheritance at the dawn of plant genetics, and continue to defy the mainstream approach to biotechnology, leading the field in an environmentally friendly direction. Recent success in engineering the chloroplast genome for resistance to herbicides, insects, disease and drought, and for production of biopharmaceuticals, has opened the door to a new era in biotechnology. The successful engineering of tomato chromoplasts for high-level transgene expression in fruits, coupled to hyper-expression of vaccine antigens, and the use of plant-derived antibiotic-free selectable markers, augur well for oral delivery of edible vaccines and biopharmaceuticals that are currently beyond the reach of those who need them most.
Copyright/Permission Statement
© <2002>. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Recommended Citation
Daniell, H., Khan, M. S., & Allison, L. (2002). Milestones in Chloroplast Genetic Engineering: an Environmentally Friendly Era in Biotechnology. Trends in Plant Science, 7 (2), 84-91. Retrieved from https://repository.upenn.edu/dental_papers/281
Date Posted: 01 March 2022
This document has been peer reviewed.
Comments
At the time of publication, author Henry Daniell was affiliated with the University of Central Florida. Currently, he is a faculty member at the School of Dental Medicine at the University of Pennsylvania