Departmental Papers (Dental)
Document Type
Journal Article
Date of this Version
4-2002
Publication Source
Current Opinion in Biotechnology
Volume
13
Issue
2
Start Page
136
Last Page
141
Abstract
Development of a rice variety enriched in provitamin A, the accumulation of polyhydroxybutyrate polyester in Arabidopsis nuclear transgenic plants (with enzymes targeted to chloroplasts in both), and the expression of bacterial operons via the chloroplast genome are recent landmark achievements in multigene engineering. Hyper-expression of transgenes has resulted in the formation of insecticidal protein crystals or inclusion bodies of pharmaceutical proteins in transgenic chloroplasts, achieving the highest level of transgene expression ever reported in transgenic plants. These achievements illustrate the potential of multigene engineering to realize benefits of the post-genomic revolution.
Copyright/Permission Statement
© <2002>. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Recommended Citation
Daniell, H., & Dhingra, A. (2002). Multigene Engineering: Dawn of an Exciting New Era in Biotechnology. Current Opinion in Biotechnology, 13 (2), 136-141. Retrieved from https://repository.upenn.edu/dental_papers/280
Date Posted: 01 March 2022
This document has been peer reviewed.
Comments
At the time of publication, author Henry Daniell was affiliated with the University of Central Florida. Currently, he is a faculty member at the School of Dental Medicine at the University of Pennsylvania