Departmental Papers (CBE)
Document Type
Journal Article
Date of this Version
November 2003
Abstract
We report the first measurements of the intrinsic strain fluctuations of living cells using a recently developed tracer correlation technique along with a theoretical framework for interpreting such data in heterogeneous media with nonthermal driving. The fluctuations’ spatial and temporal correlations indicate that the cytoskeleton can be treated as a course-grained continuum with power-law rheology, driven by a spatially random stress tensor field. Combined with recent cell rheology results, our data imply that intracellular stress fluctuations have a nearly 1/ω2 power spectrum, as expected for a continuum with a slowly evolving internal prestress.
Recommended Citation
Lau, A. W., Hoffman, B. D., Davies, A., Crocker, J. C., & Lubensky, T. C. (2003). Microrheology, Stress Fluctuations, and Active Behavior of Living Cells. Retrieved from https://repository.upenn.edu/cbe_papers/29
Date Posted: 20 December 2005
This document has been peer reviewed.
Comments
Copyright American Physical Society. Reprinted from Physical Review Letters, Volume 91, Issue 19, Article 198101, November 2003, 4 pages.
Publisher URL: http://dx.doi.org/10.1103/PhysRevLett.91.198101