Departmental Papers (CBE)

Document Type

Journal Article

Date of this Version

February 2005


The specific binding of complementary DNA strands has been suggested as an ideal method for directing the controlled self-assembly of microscopic objects. We report the first direct measurements of such DNA-induced interactions between colloidal microspheres, as well as the first colloidal crystals assembled using them. The interactions measured with our optical tweezer method can be modeled in detail by well-known statistical physics and chemistry, boding well for their application to directed selfassembly. The microspheres’ binding dynamics, however, have a surprising power-law scaling that can significantly slow annealing and crystallization.


Copyright American Physical Society. Reprinted from Physical Review Letters, Volume 94, Issue 5, Article 058302, February 2005, 4 pages.
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Date Posted: 20 December 2005

This document has been peer reviewed.