Departmental Papers (CBE)

Document Type

Technical Report

Date of this Version

5-2003

Publication Source

Molecular Therapy

Volume

7

Issue

5, Supplement

Start Page

S329

Last Page

S330

DOI

10.1016/S1525-0016(16)41295-5

Abstract

Our group has previously demonstrated stent-based gene delivery with either viral or plasmid vectors. However, these previous studies utilized bulky PLGA or collagen stent coatings, known to cause inflammatory reactions in stented arteries. In the present experiments we successfully attached adenoviruses either directly, or via anti-adenovirus antibodies to the steel surface of stents using chemical coordination with biphosphonates.

Copyright/Permission Statement

This article is published under a Creative Commons Attribution-NonCommercial-NoDerivatives license (CC BY-NC-ND).

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Date Posted: 01 December 2017

This document has been peer reviewed.