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- The process of developing a new therapeutic is long, expensive, and risky.
- Current small animal models are often poor representations of human disease, contributing to the high rate of failure in human trials.
- Outbred dogs can be excellent models for researching human disease.
- Clinical trials in dogs are inexpensive and efficient compared with human trials.
- Advaxis, a clinical-stage biotechnology company developing cancer immunotherapies, provides one case study on how trials in dogs can help advance trials in humans.
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Morrison, Alexander H.; Mason, Nicola J.; and Paterson, Yvonne
"Development Strategies for Animal Medical Therapeutics,"
Academic Entrepreneurship for Medical and Health Scientists: Vol. 1
, Article 3.
Available at: https://repository.upenn.edu/ace/vol1/iss3/3