At Penn Vet, we think differently about veterinary medicine.

In addition to providing sophisticated medical treatments for animals of every size and kind, we believe veterinarians play an integral part in ensuring public health and food safety at both local and global levels, recognizing and controlling foreign and newly emerging diseases of livestock and poultry, including diseases transmissible from animals to people.

Our mission comprises teaching, healing, and scientific investigation. We believe that as veterinarians, we not only practice medicine and conduct groundbreaking research to advance all medicine, we teach the next generation to do the same.

We believe future veterinarians should serve as the frontline, guarding against bio- and agro-terrorism and working to protect the environment, all the while advancing the forefront of biomedical research. At Penn Vet, we lead the way for veterinarians of tomorrow.

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Papers from 2016

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Assessing U.S. Food Wastage and Opportunities for Reduction, Zhengxia Dou, James D. Ferguson, David T. Galligan, Alan M. Kelly, Steven M. Finn, and Robert Giegengack

Papers from 2015

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Exclusion of the Unfolded Protein Response in Light-Induced Retinal Degeneration in the Canine T4R RHO Model of Autosomal Dominant Retinitis Pigmentosa, Stefania Marsilli, Sem Genini, Raghavi Sudharsan, Jeremy Gingrich, Gustavo D. Aguirre, and William Beltran

Papers from 2014

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Canine Retina Has a Primate Fovea-Like Bouquet of Cone Photoreceptors Which Is Affected by Inherited Macular Degenerations, William Beltran, Artur V. Cideciyan, Karina E. Guziewicz, Simone Iwabe, Erin M. Scott, Svetlana V. Savina, Gordon Ruthel, Frank Stefano, Lingli Zhang, Richard Zorger, Alexander Sumaroka, Samuel G. Jacobson, and Gustavo D. Aguirre

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Non-Equilibrium Dynamics Contribute to Ion Selectivity in the KcsA Channel, Van Ngo, Darko Stefanovski, Stephan Haas, and Robert A. Farley

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Non-Equilibrium Dynamics Contribute to Ion Selectivity in the KcsA Channel, Van Ngo, Darko Stefanovski, Stephen Haas, and Robert A. Farley

Papers from 2013

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Blinded by the Light: Retinal Phototoxicity in the Context of Safety Studies, Maria Cristina De Vera Mudry, Sven Kronenberg, Shun-ichiro Komatsu, and Gustavo D. Aguirre

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Up-Regulation of Tumor Necrosis Factor Superfamily Genes in Early Phases of Photoreceptor Degeneration, Sem Genini, William Beltran, and Gustavo D. Aguirre

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A Non-Stop S-Antigen Gene Mutation Is Associated With Late Onset Hereditary Retinal Degeneration in Dogs, Orly Goldstein, Julie Ann Jordan, Gustavo D. Aguirre, and Gregory M. Acland

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Recombinant AAV-Mediated BEST1 Transfer to the Retinal Pigment Epithelium: Analysis of Serotype-Dependent Retinal Effects, Karina E. Guziewicz, Barbara Zangerl, András M. Komáromy, Simone Iwabe, Vincent A. Chiodo, Sanford L. Boye, William W. Hauswirth, William Beltran, and Gustavo D. Aguirre

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Components of Metabolic Syndrome and 5-Year Chance in Insulin Clearance - The Resistance Atherosclerosis Study (IRAS), C. Christine Lee, Carlos Lorenzo, Steven M. Haffner, Lynne E. Wagenknecht, Mark O. Goodarzi, Darko Stefanovski, Jill M. Norris, Marian J. Rewers, and Anthony J. Hanley

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FGF19 Action in the Brain Induces Insulin-Independent Glucose Lowering, Gregory J. Morton, Miles E. Matsen, Deanna P. Bracy, Thomas H. Meek, Hong T. Nguyen, Darko Stefanovski, Richard N. Bergman, David H. Wasserman, and Michael W. Schwartz

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Exogenous Glucose Administration Impairs Glucose Tolerance and Pancreatic Insulin Secretion During Acute Sepsis in Non-Diabetic Mice, Yoshio Watanabe, Srikanth Singamsetty, Baobo Zou, Lanping Guo, Darko Stefanovski, Laura C. Alonso, Adolfo Garcia-Ocana, Christopher P. O'Donnell, and Bryan J. McVerry

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Exogenous Glucose Administration Impairs Glucose Tolerance and Pancreatic Insulin Secretion During Acute Sepsis in Non-Diabetic Mice, Yoshio Watanabe, Srikanth Singamsetty, Baobo Zou, Lanping Guo, Darko Stefanovski, Laura C. Alonso, Adolfo Garcia-Ocana, Christopher P. O'Donnell, and Bryan J. McVerry

Papers from 2012

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A Digital Atlas of the Dog Brain, Ritobrato Datta, Jongho Lee, Jeffrey Duda, Brian B. Avants, Charles H. Vite, Ben Tseng, Jim C. Gee, Gustavo D. Aguirre, and Geoffrey K. Aguirre

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Development and Validation of a Canine-Specific Profiling Array to Examine Expression of Pro-Apoptotic and Pro-Survival Genes in Retinal Degenerative Diseases, Sem Genini, William Beltran, and Gustavo D. Aguirre

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Modeling the Structural Consequences of BEST1 Missense Mutations, Karina E. Guziewicz, Gustavo D. Aguirre, and Barbara Zangerl

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Canine Multifocal Retinopathy in the Australian Shepherd: A Case Report, Ingo Hoffmann, Karina E. Guziewicz, Barbara Zangerl, Gustavo D. Aguirre, and Christian Y. Mardin

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OGTT-Derived Measures of Insulin Sensitivity Are Confounded by Factors Other Than Insulin Sensitivity Itself, Katrin Hücking, Richard M. Watanabe, Darko Stefanovski, and Richard N. Bergman

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RPGRIP1 and Cone-Rod Dystrophy in Dogs, Tatyana N. Kuznetsova, Barbara Zangerl, and Gustavo D. Aguirre

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Greater Omentectomy Improves Insulin Sensitivity in Nonobese Dogs, Maya Lottati, Cathryn M. Kolka, Darko Stefanovski, Erlinda L. Kirkman, and Richard N. Bergman

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Genetic and Phenotypic Variations of Inherited Retinal Diseases in Dogs: The Power of Within- and Across-Breed Studies, Keiko Miyadera, Gregory M. Acland, and Gustavo D. Aguirre

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Accelerating the Deactivation of Salmonella enterica Serovar Newport and Escherichia coli O157:H7 in Dairy Manure by Modifying pH or Temperature, John D. Toth, Helen W. Aceto, Shelley C. Rankin, Chitrita DebRoy, and Zhengxia Dou

Papers from 2011

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Evaluation of Adeno-Associated Viral Vectors for Liver-Directed Gene Transfer in Dogs, Peter Bell, Guangping Gao, Mark E. Haskins, Lili Wang, Margaret M. Sleeper, Huan Wang, Roberto Calcedo, Luk H. Vandenberghe, Shu-Jen Chen, Chick Weisse, Elanor Withnall, and James M. Wilson

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A Better Index of Body Adiposity, Richard N. Bergman, Darko Stefanovski, Thomas A. Buchanan, Anne E. Sumner, James C. Reynolds, Nancy G. Sebring, Anny H. Xiang, and Richard M. Watanabe

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Photoreceptor Cell Death, Proliferation and Formation of Hybrid Rod/S-Cone Photoreceptors in the Degenerating STK38L Mutant Retina, Ágnes I. Berta, Kathleen Boesze-Battaglia, Sem Genini, Orly Goldstein, Paul J. O'Brien, Ágoston Szél, Gregory M. Acland, William Beltran, and Gustavo D. Aguirre

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A Kutya Mint Modell az Örökletes Retinadegenerációk Kutatásában / The Dog as a Model in Research Into Inherited Retinal Degenerations, Ágnes I. Berta, Ágoston Szél, and Gustavo D. Aguirre

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Long-Term Systemic Myostatin Inhibition via Liver-Targeted Gene Transfer in Golden Retriever Muscular Dystrophy, Lawrence T. Bish, Margaret M. Sleeper, Sean C. Forbes, Kevin J. Morine, Caryn A. Reynolds, Gretchen E. Singletary, Dennis Trafny, Jennifer Pham, Janet Bogan, Joe N. Kornegay, Krista Vandenborne, Glenn A. Walter, and H. Lee Sweeney

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Cardiac Gene Transfer of Short Hairpin RNA Directed Against Phospholamban Effectively Knocks Down Gene Expression but Causes Cellular Toxicity in Canines, Lawrence T. Bish, Margaret M. Sleeper, Caryn A. Reynolds, Jeffrey Gazzara, Elanor Withnall, Gretchen E. Singletary, George Buchlis, Daniel Hui, Katherine A. High, Guangping Gao, James M. Wilson, and H. Lee Sweeney

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Chronic Losartan Administration Reduces Mortality and Preserves Cardiac but Not Skeletal Muscle Function in Dystrophic Mice, Lawrence T. Bish, Mark Yarchoan, Margaret M. Sleeper, Jeffrey Gazzara, Kevin J. Morine, Pedro Acosta, Elisabeth R. Barton, and H. Lee Sweeney

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Intraocular Nematodiasis in a Llama (Lama glama), Bettina Dunkel, Raymond W. Sweeney, Perry L. Habecker, and András M. Komáromy

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Transcendocardinal Delivery of AAV6 Results in Highly Efficient and Global Cardiac Gene Transfer in Rhesus Macaques, Guangping Gao, Lawrence T. Bish, Margaret M. Sleeper, Xin Mu, Lan Sun, You Lou, Jiachuan Duan, Chunyan Hu, Li Wang, and H. Lee Sweeney

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Canine Heart Failure - Early Diagnosis, Prompt Treatment, Mark A. Oyama

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Lethargy, Inappetence, & Increased Respiratory Effort in a Cat, Mark A. Oyama

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Consistency of the Disposition Index in the Face of Diet Induced Insulin Resistance: Potential Role of FFA, Darko Stefanovski, Joyce M. Richey, Orison Woolcott, Maya Lottati, Dan Zheng, Lisa N. Harrison, Viorica Ionut, Stella P. Kim, and Richard N. Bergman

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Consistency of the Disposition Index in the Face of Diet Induced Insulin Resistance: Potential Role of FFA, Darko Stefanovski, Joyce M. Richey, Orison Woolcott, Maya Lottati, Dan Zheng, Lisa N. Harrison, Viorica Ionut, Stella P. Kim, Isabel Hsu, and Richard N. Bergman

Papers from 2010

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Window Into Retinal Studies, Gustavo D. Aguirre

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rAAV2/5 Gene-Targeting to Rods: Dose-Dependent Efficiency and Complications Associated With Different Promoters, William Beltran, Sanford L. Boye, Shannon E. Boye, Vince A. Chiodo, Alfred S. Lewin, William W. Hauswirth, and Gustavo D. Aguirre

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Myostatin Is Upregulated Following Stress in an Erk-Dependent Manner and Negatively Regulates Cardiomyocyte Growth in Culture and in a Mouse Model, Lawrence T. Bish, Kevin J. Morine, Margaret M. Sleeper, and H. Lee Sweeney

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COL9A2 and COL9A3 Mutations in Canine Autosomal Recessive Oculoskeletal Dysplasia, Orly Goldstein, Richard Guyon, Anna Kukekova, Tatyana N. Kuznetsova, Susan E. Pearce-Kelling, Jennifer Johnson, Gustavo D. Aguirre, and Gregory M. Acland

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Exonic SINE Insertion in STK38L Causes Canine Early Retinal Degeneration (erd), Orly Goldstein, Anna V. Kukekova, Gustavo D. Aguirre, and Gregory M. Acland

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Systemic Myostatin Inhibition via Liver-Targeted Gene Transfer in Normal and Dystrophic Mice, Kevin J. Morine, Lawrence T. Bish, Klara Pendrak, Margaret M. Sleeper, Elisabeth R. Barton, and H. Lee Sweeney

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Overexpression of SERCA1a in the mdx Diaphragm Reduces Susceptibility to Contraction-Induced Damage, Kevin J. Morine, Margaret M. Sleeper, Elisabeth R. Barton, and H. Lee Sweeney

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Cardiac N-Terminal Pro-B-Type Natriuretic Peptide Assay, Mark A. Oyama and Gretchen E. Singletary

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Identification of Genetic Variation and Haplotype Structure of the Canine ABCA4 Gene for Retinal Disease Association Studies, Barbara Zangerl, Sarah J. Lindauer, Gregory M. Acland, and Gustavo D. Aguirre

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Assessment of Canine BEST1 Variations Identifies New Mutations and Establishes an Independent Bestrophinopathy Model (cmr3), Barbara Zangerl, Kaisa Wickström, Julianna Slavik, Sarah J. Lindauer, Saija Ahonen, Claude Schelling, Hannes Lohi, Karina E. Guziewicz, and Gustavo D. Aguirre

Papers from 2009

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Age-Dependent Disease Expression Determines Remodeling of the Retinal Mosaic in Carriers of RPGR Exon ORFn15 Mutations, William Beltran, Gregory M. Acland, and Gustavo D. Aguirre

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Steroids Do Not Prevent Photoreceptor Degeneration in the Light-Exposed T4R Rhodopsin Mutant Dog Retina Irrespective of AP-1 Inhibition, Danian Gu, William Beltran, Sue Pearce-Kelling, Zexiao Li, Gregory M. Acland, and Gustavo D. Aguirre

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Canine RD3 Mutation Establishes Rod-Cone Dysplasia Type 2 (rcd2) as Ortholog of Human and Murine rd3, Anna V. Kukekova, Orly Goldstein, Jennifer L. Johnson, Malcolm A. Richardson, Susan E. Pearce-Kelling, Anand Swaroop, James S. Friedman, Gustavo D. Aguirre, and Gregory M. Acland

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Bovine Cardiac Troponin I Gene (TNNI3) as a Candidate Gene for Bovine Dilated Cardiomyopathy, Marta Owczarek-Lipska, Gaudenz Dolf, Karina E. Guziewicz, Tosso Leeb, Claude Shelling, Horst Posthaus, and Martin H. Braunschweig

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Cardiac Drugs for Treatment of Canine Heart Failure, Mark A. Oyama

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Comparative Genomic Mapping of Uncharacterized Canine Retinal ESTs to Identify Novel Candidate Genes for Hereditary Retinal Disorders, Barbara Zangerl, Jennifer L. Johnson, Jarek Pillardy, Qi Sun, Catherine André, Francis Galibert, Gregory M. Acland, and Gustavo D. Aguirre

Papers from 2008

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Adeno-Assocated Virus (AAV) Serotype 9 Provides Global Cardiac Gene Transfer Superior to AAV1, AAV6, AAV7, and AAV8 in the Mouse and Rat, Lawrence T. Bish, Kevin J. Morine, Margaret M. Sleeper, Julio Sanmiguel, Di Wu, Guangping Gao, James M. Wilson, and H. Lee Sweeney

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Drug Delivery to Posterior Intraocular Tissues: Third Annual ARVO/Pfizer Ophthalmics Research Institute Conference, Henry F. Edelhauser, Jeffrey H. Boatright, John M. Nickerson, Third ARVO/Pfizer Research Institute Working Group, and Gustavo D. Aguirre

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Operating in the Dark: A Night-Vision System for Surgery in Retinas Susceptible to Light Damage, András M. Komáromy, Gregory M. Acland, and Gustavo D. Aguirre

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Targeting Gene Expression to Cones With Human Cone Opsin Promoters in Recombinant AAV, András M. Komáromy, John J. Alexander, Anne E. Cooper, Vince A. Chodo, Gregory M. Acland, William W. Hauswirth, and Gustavo D. Aguirre

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Cardiac Disorder in a Cat, Caryn A. Reynolds, Mark A. Oyama, and Sonya G. Gordon

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Exploring Human/Animal Intersections: Converging Lines of Evidence in Comparative Models of Aging, John Q. Trojanowski, Joan C. Hendricks, Kathryn Jedrziewski, F. Brad Johnson, Kathryn E. Michel, Rebecka S. Hess, Michael P. Cancro, Margaret M. Sleeper, Robert Pignolo, Karen L. Teff, Gustavo D. Aguirre, Virginia Man-Yee Lee, Dennis F. Lawler, Allan I. Pack, and Peter F. Davies

Papers from 2007

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Canine and Human Visual Cortex Intact and Responsive Despite Early Retinal Blindness from RPE65 Mutation, Geoffrey K. Aguirre, András M. Komáromy, Artur V. Cideciyan, David H. Brainard, Tomas S. Aleman, Alejandro J. Roman, Brian B. Avants, James C. Gee, Marc Korczykowski, William W. Hauswirth, Gregory M. Acland, Gustavo D. Aguirre, and Samuel G. Jacobson

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Intravitreal Injection of Ciliary Neurotrophic Factor (CNTF) Causes Peripheral Remodeling and Does Not Prevent Photoreceptor Loss in Canine RPGR Mutant Retina, William Beltran, Rong Wen, Gregory M. Acland, and Gustavo D. Aguirre

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AKA-TPG: A Program for Kinetic and Epidemiological Analysis of Data from Labeled Glucose Investigations Using the Two-Pool Model and Database Technology, Raymond C. Boston, Darko Stefanovski, Jan E. Henriksen, Glen M. Ward, and Peter J. Moate

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Bone Marrow Transplantation for Feline Mucopolysaccharidosis I, Norman Matthew Ellinwood, Marie-Anne Colle, Margaret A. Weil, Margret L. Casal, Charles H. Vite, Staci Wiemelt, Christopher W. Hasson, Thomas M. O'Malley, Xingxuan He, Ulana Prociuk, Lucie Verot, John R. Melniczek, Anne Lannon, Gustavo D. Aguirre, Van W. Knox, Sydney M. Evans, Marie T. Vanier, Edward H. Schuchman, Steven U. Walkley, and Mark E. Haskins

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Clinical Light Exposure, Photoreceptor Degeneration, and AP-1 Activation: A Cell Death or Cell Survival Signal in the Rhodopsin Mutant Retina?, Danian Gu, William Beltran, Zexiao Li, Gregory M. Acland, and Gustavo D. Aguirre

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Analysis of Six Candidate Genes as Potential Modifiers of Disease Expression in Canine XLPRA1, a Model for Human X-Linked Retinitis Pigmentosa 3, Richard Guyon, Susan E. Pearce-Kelling, Caroline J. Zeiss, Gregory M. Acland, and Gustavo D. Aguirre

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Bestrophin Gene Mutations Cause Canine Multifocal Retinopathy: A Novel Animal Model for Best Disease, Karina E. Guziewicz, Barbara Zangerl, Sarah J. Lindauer, Robert F. Mullins, Lynne S. Sandmeyer, Bruce H. Grahn, Edwin M. Stone, Gregory M. Acland, and Gustavo D. Aguirre

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Cloning and Characterization of Canine PAX6 and Evaluation as a Candidate Gene in a Canine Model of Aniridia, Linda S. Hunter, Duska J. Sidjanin, Manuel Villagrasa Hijar, Jennifer L. Johnson, Ewen Kirkness, Gregory M. Acland, and Gustavo D. Aguirre

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A Meiotic Linkage Map of the Silver Fox, Aligned and Compared to the Canine Genome, Anna V. Kukekova, Lyudmila N. Trut, Irina N. Oskina, Jennifer L. Johnson, Svetlana V. Temnykh, Anastasiya V. Kharlamova, Darya V. Shepeleva, Rimma G. Gulievich, Svetlana G. Shikhevich, Alexander S. Graphodatsky, Gustavo D. Aguirre, and Gregory M. Acland

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Breed Relationships Facilitate Fine-Mapping Studies: A 7.8-kb Deletion Cosegregates With Collie Eye Anomaly Across Multiple Dog Breeds, Heidi G. Parker, Anna V. Kukekova, Danya T. Akey, Orly Goldstein, Ewen F. Kirkness, Kathleen C. Baysac, Dana S. Mosher, Gustavo D. Aguirre, Gregory M. Acland, and Elaine A. Ostrander

Papers from 2006

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Linkage Disequilibrium Mapping in Domestic Dog Breeds Narrows the Progressive Rod-Cone Degeneration Interval and Identifies Ancestral Disease-Transmitting Chromosome, Orly Goldstein, Barbara Zangerl, Sue Pearce-Kelling, Duska J. Sidjanin, James W. Kijas, Jeanette Felix, Gregory M. Acland, and Gustavo D. Aguirre

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Radiation Hybrid Mapping of Cataract Genes in the Dog, Linda S. Hunter, Duska J. Sidjanin, Jennifer L. Johnson, Barbara Zangerl, Francis Galibert, Catherine Andre, Ewen Kirkness, Elijah Talamas, Gregory M. Acland, and Gustavo D. Aguirre

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Safety in Nonhuman Primates of Ocular AAV2-RPE65, a Candidate Treatment for Blindness in Leber Congenital Amaurosis, Samuel G. Jacobson, Sanford L. Boye, Tomas S. Aleman, Thomas J. Conlon, Caroline J. Zeiss, Alejandro J. Roman, Artur V. Cideciyan, Sharon B. Schwartz, András M. Komáromy, Michelle Doobrajh, Andy Y. Cheung, Alexandar Sumaroka, Susan E. Pearce-Kelling, Gustavo D. Aguirre, Shalesh Kaushal, Albert M. Maguire, Terence R. Flotte, and William W. Hauswirth

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Application of a New Subretinal Injection Device in the Dog, András M. Komáromy, Signe E. Varner, Eugene de Juan, Gregory M. Acland, and Gustavo D. Aguirre

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Dimensional Analysis of MINMOD Leads to Definition of the Disposition Index of Glucose Regulation and Improved Simulation Algorithm, Aparna Nittala, Soumitra Ghosh, Darko Stefanovski, Richard Bergman, and Xujing Wang

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Characterization of Gene Expression Profiles of Normal Canine Retina and Brain Using a Retinal cDNA Microarray, Gerardo L. Paez, Kimberly F. Sellers, Mark Band, Gregory M. Acland, Barbara Zangerl, and Gustavo D. Aguirre

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Identical Mutation in a Novel Retinal Gene Causes Progressive Rod-Cone Degeneration in Dogs and Retinitis Pigmentosa in Humans, Barbara Zangerl, Orly Goldstein, Alisdair R. Philip, Sarah J. P Lindauer, Susan E. Pearce-Kelling, Roberts F. Mullins, Alexander S. Graphodatsky, Daniel Ripoll, Jeanette S. Felix, Edwin M. Stone, Gregory M. Acland, and Gustavo D. Aguirre

Papers from 2005

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Long-Term Restoration of Rod and Cone Vision by Single Dose rAAV-Mediated Gene Transfer to the Retina in a Canine Model of Childhood Blindness, Gregory M. Acland, Gustavo D. Aguirre, Jean Bennett, Tomas S. Aleman, Artur V. Cideciyan, Jeannette Bennicelli, Nadine S. Dejneka, Susan E. Pearce-Kelling, Albert M. Maguire, Krzysztof Palczewski, William W. Hauswirth, and Samuel G. Jacobson

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Immunolocalization of Ciliary Neurotrophic Factor Receptor α (CNTFRα) in Mammalian Photoreceptor Cells, William Beltran, Hermann Rohrer, and Gustavo D. Aguirre

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Cloning of Canine Galactokinase (GALK1) and Evaluation as a Candidate Gene for Hereditary Cataracts in Labrador Retrievers, Duska J. Sidjanin, John L. McElwee, Brian Miller, and Gustavo D. Aguirre

Papers from 2004

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Acute Vascular Occlusion in Horses: Effects on Skeletal Muscle Size and Blood Flow, Takashi Abe, Charles F. Kearns, Hélio C. Manso Filho, Yoshiaki Sato, Margaret M. Sleeper, and Kenneth H. McKeever

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MINMOD Millennium: A Computer Program to Calculate Glucose Effectiveness and Insulin Sensitivity From the Frequently Sampled Intravenous Glucose Tolerance Test, Ray C. Boston, Darko Stefanovski, Peter J. Moate, Anne E. Sumner, Richard M. Watanabe, and Richard N. Bergman

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Tracheal Signs and Associated Vascular Anomalies in Dogs With Persistent Right Aortic Arch, James W. Buchanan

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Cloning of the Canine ABCA4 Gene and Evaluation in Canine Cone-Rod Dystrophies and Progressive Retinal Atrophies, James K. Kijas, Barbara Zangerl, Brian Miller, Jacque Nelson, Ewen F. Kirkness, Gustavo D. Aguirre, and Gregory M. Acland

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A Naturally Occurring Mutation of the Opsin Gene (T4R) in Dogs Affects Glycosylation and Stability of the G Protein-Coupled Receptor, Li Zhu, Geeng-Fu Jang, Beata Jastrzebska, Slawomir Filipek, Susan E. Pearce-Kelling, Gustavo D. Aguirre, Ronald E. Stenkamp, Gregory M. Acland, and Krzysztof Palczewski

Papers from 2003

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First Pacemaker in a Dog: A Historical Note, James W. Buchanan

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Etiology of Patent Ductus Arteriosus in Dogs, James W. Buchanan and Donald F. Patterson

Papers from 2002

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Cloning and Characterization of the Canine Photoreceptor Specific Cone-Rod Homeobox (CRX) Gene and Evaluation as a Candidate for Early Onset Photoreceptor Diseases in the Dog, Novrouz B. Akhmedov, Victoria J. Baldwin, Barbara Zangerl, James W. Kijas, Linda Hunter, Katayoun D. Minoofar, Cathryn Mellersh, Elaine A. Ostrander, Gregory M. Acland, Debora B. Farber, and Gustavo D. Aguirre

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Cloning and Characterization of the Canine Photoreceptor Specific Cone-Rod Homeobox (CRX) Gene and Evaluation as a Candidate for Early Onset Photoreceptor Diseases in the Dog, Novrouz B. Akhmedov, Victoria Baldwin, Barbara Zangerl, James K. Kijas, Linda S. Hunter, Katayoun D. Minoofar, Cathryn Mellersh, Elaine A. Ostrander, Gregory M. Acland, Debora B. Farber, and Gustavo D. Aguirre

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The 1st Balloon Valvuloplasty: An Historical Note, James W. Buchanan, James H. Anderson, and Robert I. White

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Therapeutic Neonatal Hepatic Gene Therapy in Mucopolysaccharidosis VII Dogs, Katherine Parker Ponder, John R. Melniczek, Lingfei Xu, Margaret A. Weil, Thomas M. O'Malley, Patricia A. O'Donnell, Van W. Knox, Gustavo D. Aguirre, Hamutal Mazrier, N Matthew Ellinwood, Margaret M. Sleeper, Albert M. Maguire, Susan W. Volk, Robert L. Mango, Jean Zweigle, John H. Wolfe, and Mark E. Haskins

Papers from 2001

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Décollement Rétinien Associé à une Cataracte Unilatérale [Retinal Detachments Associated with Unilateral Cataracts], William Beltran and Jean-Pierre Jégou

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Pathogenesis of Single Right Coronary Artery and Pulmonic Stenosis in English Bulldogs, James W. Buchanan

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An Assessment of Ammonia Emissions from Dairy Facilities in Pennsylvania, James D. Ferguson, Zhengxia Dou, and Charles F. Ramberg

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Calcium Channel Blocker D-cis-Diltiazem Does Not Slow Retinal Degeneration in the PDE6B Mutant rcd1 Canine Model of Retinitis Pigmentosa, Susan E. Pearce-Kelling, Tomas S. Aleman, Amanda Nickle, Alan M. Laties, Gustavo D. Aguirre, Samuel G. Jacobson, and Gregory M. Acland

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Posterior Segment Approach for Subretinal Transplantation or Injection in the Canine Model, Maria E. Verdugo, Julie Alling, Eliot Lazar, Manuel del Cerro, Jharna Ray, and Gustavo D. Aguirre

Papers from 2000

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Complication d'Implantation d'une Prothèse Intra-Oculaire par Prolifération d'un Adénocarcinome Iridociliaire chez un Chien [Complication of Implantation of Intraocular Prosthesis by Proliferation of an Iridociliary Adenocarcinoma in a Dog], William Beltran, Sabine Chahory, and Bernard Clerc

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Loss of Cone Molecular Markers in Rhodopsin-Mutant Human Retinas with Retinitis Pigmentosa, Sinoj K. John, Julie E. Smith, Gustavo D. Aguirre, and Ann H. Milam

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Hyphema. Part II. Diagnosis and Treatment, András M. Komáromy, David T. Ramsey, Dennis E. Brooks, Cynthia C. Ramsey, Maria E. Kallberg, and Stacy E. Andrew

Papers from 1999

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Familial Dilated Cardiomyopathy of Young Portuguese Water Dogs, Donna M. Dambach, Anne Lannon, Meg M. Sleeper, and James W. Buchanan

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Hyphema. Part I. Pathophysiologic Considerations, András M. Komáromy, David T. Ramsey, Dennis E. Brooks, Cynthia C. Ramsey, Maria E. Kallberg, and Stacy E. Andrew

Papers from 1998

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Congenital Stationary Night Blindness in the Dog: Common Mutation in the RPE65 Gene Indicates Founder Effect, Gustavo D. Aguirre, Victoria Baldwin, Sue Pearce-Kelling, Kristina Narfström, Kunal Ray, and Gregory M. Acland

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Diseases of the Retinal Pigment Epithelium-Photoreceptor Complex in Nonrodent Animal Models, Gustavo D. Aguirre, Jharna Ray, and Lawrence E. Stramm