Deformable Models with Parameter Functions for Cardiac Motion Analysis from Tagged MRI Data

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Center for Human Modeling and Simulation
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Park, Jinah
Metaxas, Dimitris
Young, Alistair A.
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We present a new method for analyzing the motion of the heart’s left ventricle (LV) from tagged magnetic resonance imaging (MRI) data. Our technique is based on the development of a new class of physics-based deformable models whose parameters are functions. They allow the definition of new parameterized primitives and parameterized deformations which can capture the local shape variation of a complex object. Furthermore, these parameters are intuitive and require no complex post-processing in order to be used by a physician. Using a physics-based approach, we convert the geometric models into dynamic models that deform due to forces exerted from the datapoints and conform to the given dataset. We present experiments involving the extraction of the shape and motion of the LV’s mid-wall during systole from tagged MRI data based on a few parameter functions. Furthermore, by plotting the variations over time of the extracted LV model parameters from normal and abnormal heart data along the long axis, we are able to quantitatively characterize their differences.

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1996-06-01
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Copyright 1996 IEEE. Reprinted from IEEE Transactions on Medical Imaging, Volume, 15, Issue 3, June 1996, pages 278-289. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of the University of Pennsylvania's products or services. Internal or personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution must be obtained from the IEEE by writing to pubs-permissions@ieee.org. By choosing to view this document, you agree to all provisions of the copyright laws protecting it.
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