Penn Dental Medicine views scholarship as a central component of excellence in instruction and patient care and places a high priority on research. The School’s research enterprise spans scientific disciplines to translate new knowledge into clinical therapies that positively impact our understanding of oral disease and advance patient care.

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Submissions from 2016

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Penn Endo Surgical Documentation Guidelines, Bekir Karabucak

Submissions from 2014

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Role of Fas and Treg Cells in Fracture Healing as Characterized in the Fas-Deficient (lpr) Mouse Model of Lupus, Maisa O. Al-Sebaei, Dana M. Daukss, Anna C. Belkina, Sanjeev Kakar, Nathan A. Wigner, Daniel Crusher, Dana T. Graves, Thomas Einhorn, Elise Morgan, and Louis C. Gerstenfeld

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Effect of Bacteria on the Wound Healing Behavior of Oral Epithelial Cells, Rupa Bhattacharya, Fanxing Xu, Guangyu Dong, Shuai Li, Chen Tian, Bhaskar Ponugoti, and Dana T. Graves

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FOXO1, TGF-β Regulation and Wound Healing, Alhassan Hameedaldeen, Jian Liu, Angelika Batres, Gabrielle S. Graves, and Dana T. Graves

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A Comparison of Dimensional Standard of Several Nickel-Titanium Rotary Files, Ki-Won Kim, Kyung-Mo Cho, Se-Hee Park, Ki-Yeol Choi, Bekir Karabucak, and Jin-Woo Kim

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FOXO Transcription Factors: Their Clinical Significance and Regulation, Yu Wang, Yanmin Zhou, and Dana T. Graves

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Wnt4 Signaling Prevents Skeletal Aging and Inflammation by Inhibiting Nuclear Factor-κB, Bo Yu, Jia Chang, Jiong Li, Kareena Kevork, Khalid Al-Hezaimi, Dana T. Graves, No-Hee Park, and Cun-Yu Wang

Submissions from 2013

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Chemokine Expression Is Upregulated in Chondrocytes in Diabetic Fracture Healing, Jazia Alblowi, Chen Tian, Rayyan A. Kayal, Erin McKenzie, Yugal Behl, Louis Gerstenfeld, Thomas A. Einhorn, and Dana T. Graves

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An Evaluation of 10 Percent and 20 Percent Benzocaine Gels in Patients With Acute Toothaches: Efficacy, Tolerability and Compliance With Label Dose Administration Directions, Elliot V. Hersh, Sebastian G. Ciancio, Arthur S. Kuperstein, Eric T. Stoopler, Paul A. Moore, Sean G. Boynes, Steven C. Levine, Paul Casamassimo, Rina Leyva, Tanya Mathew, Othman Shibly, Paul Creighton, Gary E. Jeffers, Patricia M. A Corby, Stanley N. Turetzky, Athena Papas, Jillian Wallen, Cynthia Idzik-Starr, and Sharon M. Gordon

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P. gingivalis Modulates Keratinocytes Through FOXO Transcription Factors, Shuai Li, Guangyu Dong, Anastasios Moschidis, Javier Ortiz, Manjunatha R. Benakanakere, Denis F. Kinane, and Dana T. Graves

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FOXO1 Promotes Wound Healing Through the Up-Regulation of TGF-β1 and Prevention of Oxidative Stress, Bhaskar Ponugoti, Fanxing Xu, Chenying Zhang, Chen Tian, Sandra Pacios, and Dana T. Graves

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Pemphigus, Frank A. Santoro, Eric T. Stoopler, and Victoria P. Werth

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Topical and Systemic Therapies for Oral and Perioral Herpes Simplex Virus Infections, Eric T. Stoopler and Ramesh Balasubramanlam

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Glossitis Secondary to Vitamin B12 Deficiency Anemia, Eric T. Stoopler and Arthur S. Kuperstein

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Recurrent Aphthous Stomatitis, Eric T. Stoopler and Thamer Musbah

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Household Laundry Detergent as a Possible Cause of Oral Lichenoid Lesions, Eric T. Stoopler and Christine Nadeau

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Temporomandibular Disorders, Eric T. Stoopler and Thomas P. Sollecito

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Locally Delivered Salicylic Acid From a Poly(anhydride-ester): Impact on Diabetic Bone Regeneration, Keisuke Wada

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Abnormal Cell Repsonses and Role of TNF-α in Impaired Diabetic Wound Healing, Fanxing Xu, Chenying Zhang, and Dana T. Graves

Submissions from 2012

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Animal Models to Study Host-Bacteria Interactions Involved in Periodontitis, Dana T. Graves, Jun Kang, Oelisoa Andriankaja, Keisuke Wada, and Carlos Rossa Jr.

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Role of Forkhead Transcription Factors in Diabetes-Induced Oxidative Stress, Bhaskar Ponugoti, Guangyu Dong, and Dana T. Graves

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Pregnancy Gingivitis and Pregnancy Tumour, Eric T. Stoopler and Arthur S. Kuperstein

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Oral Lichen Planus, Eric T. Stoopler and Thomas P. Sollecito

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Effect of Body Composition and Renal Function on the Pharmacokinetics of High-Dose Melphalan for Multiple Myeloma, Dan T. Vogl, Rosemarie Mick, Eric T. Stoopler, Lisa E. Davis, Thomas M. Paul, German Salazar, Maria Raguza-Lopez, David L. Porter, Selina M. Luger, and Edward A. Stadtmauer

Submissions from 2011

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Review of Osteoimmunology and the Host Response in Endodontic and Periodontal Lesions, Dana T. Graves, Thomas Oates, and Gustavo P. Garlet

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A Long-Term siRNA Strategy Regulates Fibronectin Overexpression and Improves Vascular Lesions in Retinas of Diabetic Rats, Sumon Roy, Sigrid Nasser, Dana T. Graves, and Sayon Roy

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FOXO1 Modulates Osteoblast Differentiation, Michelle F. Siqueira, Stephen Flowers, Rupa Bhattacharya, Dan Faibish, Yugal Behl, Darrell N. Kotton, Lou Gerstenfeld, Elizabeth Moran, and Dana T. Graves

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Human Papillomavirus Lesions of the Oral Cavity, Eric T. Stoopler and Ramesh Balasubramanlam

Submissions from 2010

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FOXO1 Plays an Essential Role in Apoptosis of Retinal Pericytes, Mani Alikhani, Sayon Roy, and Dana T. Graves

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Impaired Wound Healing in Mouse Models of Diabetes Is Mediated by TNF-α Dysregulation and Associated With Enhanced Activation of Forkhead Box O1 (FOXO1), Michelle F. Siqueira, Jingyuan Li, Leena Chehab, Tesfahun Desta, Takahiro Chino, N. Krothpali, Yugal Behl, Mani Alikhani, Julia Yang, Cameron Braasch, and Dana T. Graves

Submissions from 2009

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BMP2 Is Essential for Post Natal Osteogenesis but Not for Recruitment of Osteogenic Stem Cells, Manish V. Bais, Nathan A. Wigner, Megan Young, Ryan Toholka, Dana T. Graves, Elise Feng Morgan, Louis Charles Gerstenfeld, and Thomas A. Einhorn

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Functional and Structural Characterization of Chimeras of a Bacterial Genotoxin and Human Type I DNAse, Joseph M. DiRienzo, Linsen Cao, Alla Volgina, Georges Bandelac, and Johnathan M. Korostoff

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Diabetes Causes the Accelerated Loss of Cartilage During Fracture Repair Which Is Reversed by Insulin Treatment, Rayyan A. Kayal, Jazia Alblowi, Erin McKenzie, Nanarao Krothapalli, Lee Silkman, Louis Gerstenfeld, Thomas Einhorn, and Dana T. Graves

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Evaluation of the Humoral Immune Response to the Cytolethal Distending Toxin of Aggregatibacter Actinomycetemcomitans Y4 in Subjects With Localized Aggressive Periodontitis, Ioanna Xynogala, Alla Volgina, Joseph M. DiRienzo, and Johnathan M. Korostoff

Submissions from 2008

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Molecular Mechanisms Controlling Bone Formation During Fracture Healing and Distraction Osteogenesis, Zainab S. Al-Aql, Adel S. Alagl, Dana T. Graves, Louis C. Gerstenfeld, and Thomas A. Einhorn

Submissions from 2007

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Advanced Glycation End Products Stimulate Osteoblast Apoptosis Via the MAP Kinase and Cytosolic Apoptotic Pathways, Mani Alikhani, Zoubin Alikhani, Coy Boyd, Christine M. McLellan, Markos Raptis, Rongkun Liu, Nicole Pischon, Philip C. Trackman, Louis Gerstenfeld, and Dana T. Graves

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Apoptosis in Gingival Overgrowth Tissues, Alpdoǧan I. Kantarci, Peter Augustín, Erhan Firatli, Michael C. Sheff, Hatice Hastürk, Dana T. Graves, and Philip C. Trackman

Submissions from 2006

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Diabetes Enhances Periodontal Bone Loss Through Enhanced Resorption and Diminished Bone Formation, Rongkun Liu, Harbinder S. Bal, Tesfahun Desta, Nanarao Krothapalli, Monaf Alyassi, Qingxian Luan, and Dana T. Graves

Submissions from 2005

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Characterization of Point Mutations in the cdtA Gene of the Cytolethal Distending Toxin of Actinobacillus Actinomycetemcomitans, Linsen Cao, Alla Volgina, Chuang-ming Huang, Johnathan M. Korostoff, and Joseph M. DiRienzo

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Differential Effect of the Cytolethal Distending Toxin of Actinobacillus actinomycetemcomitans on Co-Cultures of Human Oral Cells, Philip Kang, Johnathan M. Korostoff, Alla Volgina, Wojciech Grzesik, and Joseph M. DiRienzo

Submissions from 2003

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Extensive Pneumatization of the Temporal Bone and Articular Eminence: An Incidental Finding in a Patient With Facial Pain. Case Report and Review of Literature, Eric T. Stoopler, Andres A. Pinto, David C. Stanton, Muralidhar Mupparapu, and Thomas P. Sollecito

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Desquamative Gingivitis: Early Presenting Symptom of Mucocutaneous Disease, Eric T. Stoopler, Thomas P. Sollecito, and Scott S. DeRossi

Submissions from 1990

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Neonatal Exposure to Thymotropic Gross Murine Leukemia Virus Induces Virus-Specific Immunologic Nonresponsiveness, Johnathan M. Korostoff, Marian T. Nakada, Susan J. Faas, Kenneth J. Blank, and Glen N. Gaulton